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MetabolomicsSuboxic DOM is bioavailable to surface prokaryotes in a simulated overturn of an oxygen minimum zone, Devil’s Hole, Bermuda
Oxygen minimum zones (OMZs) are expanding due to increased sea surface temperatures, subsequent increased oxygen demand through respiration, reduced oxygen solubility, and thermal stratification driven in part by anthropogenic climate change. Devil's Hole, Bermuda is a model ecosystem to study OMZ m...
2024-02-27 | MTBLS8122 | MetaboLights
MetabolomicsDissolved metabolites from the Bermuda Atlantic Time-series Study: 2016-2019

Organic carbon in seawater plays a significant role in the global carbon cycle. The concentration and composition of dissolved organic carbon, operationally defined in this project as organic carbon that passes through a 0.2 µm filter, reflect the actions of the biological community and chemical ...

2022-02-09 | MTBLS2356 | MetaboLights
MetabolomicsDifferent carboxyl-rich alicyclic molecules proxy compounds select distinct bacterioplankton for oxidation of dissolved organic matter in the mesopelagic Sargasso Sea

Marine dissolved organic matter (DOM) varies in its recalcitrance to rapid microbial degradation. DOM of varying recalcitrance can be exported from the ocean surface to depth by subduction or convective mixing and oxidized over months to decades in deeper seawater. Carboxyl-rich alicyclic molecul...

2024-02-20 | MTBLS3512 | MetaboLights
MetabolomicsMigratory Zooplankton Excreta and its Influence on Prokaryotic Communities

Particulate organic matter (fecal pellets) from zooplankton has been demonstrated to be important nutrient sources for the pelagic prokaryotic community. Significantly less is known about the chemical composition of the dissolved organic matter (DOM) produced by these eukaryotes and its infl...

2020-11-27 | MTBLS1822 | MetaboLights
ProteomicsHuman kidney proteomics, glomerular and tubular cellular and matrix fractions
Glomerular and tubulointerstitial fractions were enriched from human kidneys samples. Ages of human kidney samples: 15, 29, 37, 61, 67 and 69 years of age. The glomerular and tubulointerstitial samples were processed to enrich for extracellular matrix components and the fractions analysed by mass sp...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD022219 | Pride
Tubulointerstitial Tubular Glomerular Kidney Age 
ProteomicsProteomic analysis of healthy and hyperglycemic murine fetal kidneys
Alteration of kidney morphogenesis in diabetic pregnancies is poorly described, especially changes in the extracellular matrix (ECM) and glomerular basement membrane (GBM during glomerulogenesis. Addressing the ECM proteome, or matrisome, in the mouse fetal kidney in a healthy and diabetic environme...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-13 | PXD025874 | Pride
Mass spectrometry Basement membrane Enrichment Kidney Extracellular matrix Diabetes 
ProteomicsProteomic analysis of induced pluripotent stem cell-derived kidney organoids
Kidney organoids were generated from a control iPSC line using a previously published protocol (https://doi.org/10.1038/nprot.2016.098). Organoids were collected at three timepoints during the protocol (day 14, 18 and 25) and prepared for proteomic analyses. The focus of the study was to define the ...
ORGANISM(S): Homo sapiens (Human) 
2021-10-13 | PXD025838 | Pride
Mass spectrometry Basement membrane Kidney organoid Enrichment Kidney Extracellular matrix 
UnknownDexamethasone in Hospitalized Patients with Covid-19.
Not available
S-EPMC7383595 | biostudies-literature
UnknownEffect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
Not available
S-EPMC7556338 | biostudies-literature
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