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ModelsAbuOun2009 - Genome-scale metabolic network of Salmonella typhimurium (iMA945)
AbuOun2009 - Genome-scale metabolic network of Salmonella typhimurium (iMA945) This model is described in the article: Genome scale reconstruction of a Salmonella metabolic model: comparison of similarity and differences with a commensal Escherichia coli strain. AbuOun M, Suth...
2015-07-30 | MODEL1507180009 | BioModels
TranscriptomicsThe transcriptomic response of E. coli to triclosan exposure
The gene expression profile of E. coli K-12 MG1655 grown in minimal medium treated with 0.12 mg/L of the biocide triclosan has been analysed using whole genome oligonucleotide microarrays. "Control" RNA was isolated from three independently grown 50ml MOPS minimal media cultures of E. coli K-12 MG16...
ORGANISM(S): Escherichia coli 
2010-10-08 | E-GEOD-15059 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse cerebral cortex using two model strains (C57BL/6 and ApoE(-/-) on the C57BL background) upon episode hypoxia treatment
Study the gene expression variation at cerebral cortex using two mouse model strains (C57BL/6 and ApoE(-/-) on the C57BL background) upon episode hypoxia treatment
ORGANISM(S): Mus musculus 
2013-01-30 | E-TIGR-135 | biostudies-arrayexpress
UnknownAdjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer.

Background

Pertuzumab increases the rate of pathological complete response in the preoperative context and increases overall survival among patients with metastatic disease when it is added to trastuzumab and chemotherapy for the treatment of human epidermal growth factor receptor 2 (HER2)-p...
S-EPMC5538020 | biostudies-literature
UnknownPregnancy and neonatal outcomes of COVID-19: The PAN-COVID study.

Objective

To assess perinatal outcomes for pregnancies affected by suspected or confirmed SARS-CoV-2 infection.

Methods

Prospective, web-based registry. Pregnant women were invited to participate if they had suspected or confirmed SARS-CoV-2 infection between 1st January 2020 and 31st...
S-EPMC9295331 | biostudies-literature
UnknownBiallelic variants in ribonuclease inhibitor (RNH1), an inflammasome modulator, are associated with a distinctive subtype of acute, necrotizing encephalopathy.

Purpose

Mendelian etiologies for acute encephalopathies in previously healthy children are poorly understood, with the exception of RAN binding protein 2 (RANBP2)-associated acute necrotizing encephalopathy subtype 1 (ANE1). We provide clinical, genetic, and neuroradiological evidence that b...
S-EPMC10506156 | biostudies-literature
UnknownWhole-genome sequencing of patients with rare diseases in a national health system.
Most patients with rare diseases do not receive a molecular diagnosis and the aetiological variants and causative genes for more than half such disorders remain to be discovered1. Here we used whole-genome sequencing (WGS) in a national health system to streamline diagnosis and to discove...
S-EPMC7610553 | biostudies-literature
UnknownGWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements.
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disorder affecting 0.5-2% of pregnancies. The majority of cases present in the third trimester with pruritus, elevated serum bile acids and abnormal serum liver tests. ICP is associated with an increased risk of adverse outcom...
S-EPMC9385867 | biostudies-literature
UnknownGenome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory arthritis. By combining data from >140,000 individuals of European ancestry within the Global Urate Genetics Consortium (GUGC), we identified and replicated 28 genome-wide significant loci in association with se...
S-EPMC3663712 | biostudies-literature
UnknownTherapeutic Hypothermia after In-Hospital Cardiac Arrest in Children.

Background

Targeted temperature management is recommended for comatose adults and children after out-of-hospital cardiac arrest; however, data on temperature management after in-hospital cardiac arrest are limited.

Methods

In a trial conducted at 37 children's hospitals, we compared t...
S-EPMC5310766 | biostudies-literature
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