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TranscriptomicsDefinition of the AmrZ regulon under a twitching-promoting condition
A novel approach using cellophane sheets was designed to promote Pseudomonas aeruginosa twitching motility, as well as to provide convenience for cell harvest. The AmrZ regulon was defined under this specific growth condition by microarray analysis. WT P. aeruginosa and amrZ mutants were cultivated ...
ORGANISM(S): Pseudomonas aeruginosa 
2015-09-06 | E-GEOD-68066 | biostudies-arrayexpress
TranscriptomicsExpression data from serum-stimulated NIH 3T3 cells stably expressing control (pLKO.1) vector or shRNAs targeting Net or Sap-1
Although much is known about focal adhesion signaling induced by cell adhesion, how adhesion directs changes in transcription to control cell behavior is far less understood. Here we describe a novel mechanism by which changes in adhesion switch the activities of the mitogen-activated protein kinas...
ORGANISM(S): Mus musculus 
2013-01-01 | E-GEOD-26640 | biostudies-arrayexpress
ProteomicsMabscessus_Antibiotics_Proteomic_Analysis
Quantitative proteome of M. Abscessus in various experimental conditions.
ORGANISM(S): Mycobacterium Abscessus Atcc 19977 (ncbitaxon:561007) 
2020-05-03 | MSV000085363 | MassIVE
TranscriptomicsMethylation profiling of normal and cancerous human breast samples
To assess changes in DNA methylation state associated with breast cancer we analyzed DNA from normal and cancerous breast specimens on CpG islands microarray using methylation-sensitive enzyme McrBC for target preparation. Cy3 was used for McrBC cut sample, Cy5 was used for reference Mock sample.
ORGANISM(S): Homo sapiens 
2006-11-03 | E-MEXP-881 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of normal and cancerous breast cells from human patients and cell lines in a 125 kB region of the HOXA cluster
To evaluate DNA methylation profile associated with breast cancer in 125 kB region of HOXA cluster we analyzed DNA from normal cancerous breast specimens and cell lines. Analysis was performed on the tiling array covering entire HOXA region with 500bp resolution. Immunoprecipitation with anti-methyl...
ORGANISM(S): Homo sapiens 
2006-11-03 | E-MEXP-880 | biostudies-arrayexpress
TranscriptomicsMetastatic potential is determined early in synovial sarcoma development and reflected by tumor molecular features [aCGH]
Synovial sarcoma (SynSa) is an aggressive mesenchymal tumor, comprising approximately 10% of all soft tissue sarcomas. Over half of SynSa patients develop metastasis or local recurrence, but the underlying molecular mechanisms of the aggressive clinical behavior remain poorly characterized. Sixty f...
ORGANISM(S): Homo sapiens 
2014-07-31 | E-GEOD-54183 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of human peripheral T cell lymphoma cases vs. reactive lymph nodes
Peripheral T cell lymphoma (PTCL) is a very aggressive disease which currently lacks efficient targeted therapy. New therapeutic strategies are needed to improve the very poor outcome of these patients. However, little is known about the molecular pathogenesis of this disease. In this study, we perf...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-36172 | biostudies-arrayexpress
TranscriptomicsMetastatic potential is determined early in synovial sarcoma development and reflected by tumor molecular features [transcriptome]
Synovial sarcoma (SynSa) is an aggressive mesenchymal tumor, comprising approximately 10% of all soft tissue sarcomas. Over half of SynSa patients develop metastasis or local recurrence, but the underlying molecular mechanisms of the aggressive clinical behavior remain poorly characterized. Sixty f...
ORGANISM(S): Homo sapiens 
2014-07-31 | E-GEOD-54187 | biostudies-arrayexpress
TranscriptomicsRNA-seq of a controlled porcine model of trauma and haemorrhagic shock treated by fluid resuscitation against untreated controls
This was a randomised study in terminally anaesthetised female cross-bred Large White pigs. Initially, animals were anaesthetised and instrumented for continuous physiological monitoring and sampling; blood samples were collected upon initiation of the surgery (line-in, T = -150 minutes). Following ...
ORGANISM(S): Sus scrofa 
2026-10-28 | E-MTAB-16011 | biostudies-arrayexpress
TranscriptomicsMetastatic potential is determined early in synovial sarcoma development and reflected by tumor molecular features
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-07-31 | E-GEOD-54188 | biostudies-arrayexpress
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