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GenomicsHistone H3, lysine 27 acetylation ChIP-seq in NALM6 expressing ETV6-RUNX1
ETV6-RUNX1 is a fusion protein bringing together almost the entire coding sequence of RUNX1, including the DNA binding runt domain, and the N-terminus of ETV6 which is known to include transcriptional repressors including histone deacetylation 3 (HDAC3). Here we perform ChIP-seq for the active chrom...
ORGANISM(S): Homo sapiens 
2022-10-31 | E-MTAB-12207 | biostudies-arrayexpress
TranscriptomicsGene expression data from induced Pluripotent Stem cells from Parkinson's Disease patients harbouring amplification of, or mutations in the SNCA gene, and from healthy control donors [gene expression]
We have generated human induced Pluripotent Stem cells (hiPSc) using Sendai virus-mediated delivery of reprogramming factors. hiPSc lines have been screened using SNP array to assess chromosomal stability (alongside the fibroblast lines from which they derived), and validation of the pluripotency of...
ORGANISM(S): Homo sapiens 
2016-11-16 | GSE89883 | GEO
TranscriptomicsGenetics of gene expression responses to temperature stress in a sea urchin gene network (HTS)
Stress responses play an important role in shaping species distributions and robustness to climate change. We investigated how stress responses alter the contribution of additive genetic variation to gene expression during development of the purple sea urchin, Strongylocentrotus purpuratus, under in...
ORGANISM(S): Strongylocentrotus purpuratus 
2012-11-30 | E-GEOD-38606 | biostudies-arrayexpress
UnknownParaneoplastic upbeat nystagmus.
Not available
S-EPMC3159092 | biostudies-literature
ProteomicsProteomic analysis of sea urchin egg provisioning and development
Here we present LC-MS/MS proteomic datasets of Heliocidaris erythrogramma, Heliocidaris tuberculata, and Lytechinus variegatus eggs and larvae. We find dramatic proteomic differences likely associated with life history evolution and between developmental stages. This study provides a complimentary d...
ORGANISM(S): Lytechinus variegatus Heliocidaris erythrogramma (Sea urchin) Heliocidaris tuberculata 
2019-03-04 | PXD007065 | Pride
Developmental stage Sea urchin 
UnknownHealth Service Utilization Patterns Among Medicaid Enrollees With Intellectual and Developmental Disabilities Before and During the COVID-19 Pandemic: Implications for Pandemic Response and Recovery Efforts.
Not available
S-EPMC11441349 | biostudies-literature
UnknownDisruption of lipid-raft localized Gαs/tubulin complexes by antidepressants: a unique feature of HDAC6 inhibitors, SSRI and tricyclic compounds.
Not available
S-EPMC5983546 | biostudies-literature
ProteomicsStructures reveal DnaA domain I dimer conserved across Actinomycetes: implications for replication initiation
DNA replication is a fundamental process in biology with initiation marking its key, first step. In bacteria, DNA replication is initiated by the DnaA protein. DnaA exhibits multidomain architecture, consisting of an N-terminal domain I, linker region, AAA+ family ATPase cassette, and C-terminal DN...
ORGANISM(S): Homo sapiens (Human) 
2026-05-27 | PXD074705 | Pride
Hdx ms  dnaa  dimerization  dna replication  dimeric interface  hydrogen/deuterium exchange mass spectrometry 
UnknownMass spectrometry analysis of tau and amyloid-beta in iPSC-derived models of Alzheimer's disease and dementia.
Not available
S-EPMC8613538 | biostudies-literature
UnknownAccelerated neuronal and synaptic maturation by BrainPhys medium increases Aβ secretion and alters Aβ peptide ratios from iPSC-derived cortical neurons.
Not available
S-EPMC6969066 | biostudies-literature
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