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GenomicsPdx1 occupancy during mouse and human development
The aim of this study is to identify sites occupied by Pdx1 throughout key stages in mouse and human pancreatic development as well as during in vitro differentiation of human ES cells.
ORGANISM(S): Mus musculus 
2018-01-02 | E-MTAB-3354 | biostudies-arrayexpress
GenomicsRegulatory genomics of human embryonic pancreatic progenitors
Active regulatory regions in the human embryonic pancreatic progenitors were profiled by integration of transcription factor and histone modification ChIP-seq datasets. These were obtained from pancreatic progenitor cells derived in vitro from human embryonic stem cells. The purpose of this work was...
ORGANISM(S): Homo sapiens 
2013-11-15 | E-MTAB-1990 | biostudies-arrayexpress
TranscriptomicsGene expression changes in the female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury
Methylmercury (MeHg) is a potent neurotoxin and endocrine disruptor that accumulates in aquatic systems. Previous studies have shown suppression of hormone levels in both male and female fish, suggesting effects on gonadotropin regulation in the brain. We investigated the gene expression profile in ...
ORGANISM(S): Danio rerio 
2010-09-30 | E-GEOD-22662 | biostudies-arrayexpress
TranscriptomicsS. pombe acetyltransferase mutants identifies redundant pathways of gene regulation, dual-channel dataset
Analysis of histone acetyl transferases (HATs) from the MYST and GNAT families in S. pombe to identify functional differences or overlap with regard to gene expression. Mutations were made to Elp3 and Gcn5 (GNAT family), and to Mst2 (MYST family). Mutants showed distinct phenotypes which were repres...
ORGANISM(S): Schizosaccharomyces pombe 
2009-09-19 | E-GEOD-17259 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse E15.5 FACS sorted pancreas populations based on double fluorescent reporter (Hes1GFP and Neurog3-RFP), DBA staining and Ptf1a-YFP.
In order to generate a comprehensive map of differentially expressed genes in embryonic mouse pancreas cell types on which to map results from later analyses, we first performed microarray-based gene expression profiling of purified E15.5 pancreas cell populations. We isolated GFP+RFP−DBA+, GFP+RFP+...
ORGANISM(S): Mus musculus 
2018-09-10 | E-MTAB-6891 | biostudies-arrayexpress
UnknownAn open-source bio-logger for studying cetacean behavior and communication.
Not available
S-EPMC12697950 | biostudies-literature
TranscriptomicsProfiling of Human Adipose Tissue and Effect of Sibutramine on Gene Expression
We analyzed the expression of 23,653 transcripts in the adipose tissue of 19 individuals treated with Sibutramine Keywords: sibutramine effect 157 adipose tissue samples from 19 individuals treated with sibutramin as well as placebo were profiled for gene expression.
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-10545 | biostudies-arrayexpress
UnknownAntepartum SARS-CoV-2 infection and adverse birth outcomes in South African women.
Not available
S-EPMC9718447 | biostudies-literature
GenomicsTEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors
The genomic regulatory programs that underlie human organogenesis are poorly understood. Human pancreas development, in particular, has pivotal implications for pancreatic regeneration, cancer, and diabetes. We have now created maps of transcripts, active enhancers, and transcription factor networks...
ORGANISM(S): Homo sapiens 
2015-04-06 | E-MTAB-3061 | biostudies-arrayexpress
GenomicsA Genomic History of Aboriginal Australia
The population history of Aboriginal Australians remains largely uncharacterised. We generated high-coverage genomes for 83 Aboriginal Australians (speakers of Pama-Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25...
EGAS00001001766 | EGA
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