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ProteomicsEffect of water emersion on the gill proteome of Mangrove killifish
Gill proteome of Mangrove killifish was compared by LC-MS/MS using 6 biological replicates of fish exposed to emersion stress versus 6 biological replicates kept under water that served as controls. PI: Experiments and fish exposures were performed in the laboratory of Prof. Patricia Wright at the U...
ORGANISM(S): Kryptolebias Marmoratus (ncbitaxon:37003) 
2017-03-15 | MSV000080634 | MassIVE
GenomicsEGAS00001000775-sc-2023-03-15T11:18:45Z - samples
Candidate diagnostic variants reported into DECIPHER by 4 April 2022, annotated with clinical and automated pathogenicity assertions (see DOI: 10.1056/NEJMoa2209046). Genomic Diagnosis of Rare Pediatric Disease in the United Kingdom and Ireland, Wright et al, NEJM 2023.
EGAD00001010137 | EGA
TranscriptomicsTranscriptional changes in IL-2, IL-12 and IL-18 stimulated human natural killer cells
We used Affymetrix expression arrays to determine changes in gene expression associated with activation of human NK cells mediated through treatment with cytokines IL-2, IL-12 and IL-18 over a 24 hour period. Human natural killer cells were isolated via negative selection from PBMCs of healthy donor...
ORGANISM(S): Homo sapiens 
2010-08-05 | E-GEOD-22919 | biostudies-arrayexpress
ProteomicsATPase activity in Plasmodium falciparum asexual blood stages and gametocytes
Characterization of ATPase activity associated with gametocytogenesis in P. falciparum
ORGANISM(S): Plasmodium falciparum 
2017-10-31 | PXD005335 | Pride
Malaria Activity-based proteomics Atpase 
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
TranscriptomicsTranscription profiling by array of mouse jejunum cells of FVB/N wild type and Lrig1 knockout littermates
Transcriptional profiling of jejunum (middle intestine) cells of FVB/N mice and Lrig1 knockout littermates.
ORGANISM(S): Mus musculus 
2012-03-05 | E-MTAB-378 | biostudies-arrayexpress
TranscriptomicsDNA copy number profiling of canine osteosarcoma
Identification of DNA copy number imbalances in 22 spontaneous canine osteosarcoma cases using array comparative genomic hybridization (aCGH) analysis
ORGANISM(S): Canis familiaris 
2013-11-01 | E-MTAB-1986 | biostudies-arrayexpress
GenomicsChIP-seq Accurately Predicts Tissue-Specific Activity of Enhancers
Determining the spatial and temporal activity patterns of enhancers remains a challenge in the functional annotation of the human genome. Here, we performed genome-wide mapping of tissue-specific in vivo binding sites for the enhancer-associated protein p300 and assessed in transgenic mice the util...
ORGANISM(S): Mus musculus 
2009-02-11 | E-GEOD-13845 | biostudies-arrayexpress
GenomicsLarge-Scale Discovery of Enhancers from Human Heart Tissue
Development and function of the human heart depend on the dynamic control of tissue-specific gene expression by distant-acting transcriptional enhancers. While large numbers of heart enhancers have been identified using the mouse as a model system, many of these regulatory sequences are poorly cons...
ORGANISM(S): Mus musculus 
2011-12-04 | E-GEOD-32587 | biostudies-arrayexpress
TranscriptomicsInduction of hepatocellular carcinoma through activation of stromal cells in Pdgf-c transgenic mice
Liver cirrhosis is a strong risk factor for the development of hepatocellular carcinoma (HCC), yet the mechanisms by which cirrhosis predisposes patients to tumorigenesis are not well understood. Transgenic mice expressing platelet-derived growth factor C (Pdgf-c) under the control of the albumin pr...
ORGANISM(S): Mus musculus 
2014-05-12 | E-GEOD-38199 | biostudies-arrayexpress
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