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UnknownWSB-1 regulates the metastatic potential of hormone receptor negative breast cancer.
Not available
S-EPMC5943535 | biostudies-literature
GenomicsCandidate Gene Identification Through RNA-Seq Analysis of (TRAMP x WSB/EiJ) F2 Primary Tumors
Candidate Gene Identification Through RNA-Seq Analysis of (TRAMP x WSB/EiJ) F2 Primary Tumors
PRJNA422530 | ENA
TranscriptomicsTestis expression in Mus musculus domesticus WSB/EiJ x Mus musculus musculus PWD/PhJ F2 hybrids
To characterize the genetic basis of hybrid male sterility in detail, we used a systems genetics approach, integrating mapping of gene expression traits with sterility phenotypes and QTL. We measured genome-wide testis expression in 305 male F2s from a cross between wild-derived inbred strains of M....
ORGANISM(S): Mus musculus 
2014-05-01 | E-GEOD-54089 | biostudies-arrayexpress
TranscriptomicsInterstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism.
Nonalcoholic fatty liver disease (NAFLD) is a major health problem and a leading cause of chronic liver disease in the United States and developed countries. In humans, genetic factors greatly influence individual susceptibility to NAFLD. The goals of this study were to compare the magnitude of inte...
ORGANISM(S): Mus musculus 
2014-10-16 | E-GEOD-62362 | biostudies-arrayexpress
UnknownThe Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate.
Not available
S-EPMC1761694 | biostudies-literature
GenomicsMus musculus breed:CAST/WSB
Mus musculus breed:CAST/WSB Raw sequence reads
PRJNA280976 | ENA
TranscriptomicsCandidate Gene Identification Through RNA-Seq Analysis of (TRAMP x WSB/EiJ) F2 Primary Tumors
RNA-seq analysis of 115 randomly selected (TRAMP x WSB/EiJ) F2 prostates that had been harvested at experimental termination was performed to identify metastasis associated transcriptomic changes
ORGANISM(S): Mus musculus 
2018-05-14 | GSE108131 | GEO
TranscriptomicsMultiple tissue expression data from inbreds and F1 of CAST, PWK, and WSB
We create catalogues of genes showing significant strain, parent-of-origin, dominance, sex effect in inbreds and reciprocal F1 hybrids of three wild-derived strains (CAST, PWK, WSB) across 4 different tissues (brain, kidney, liver, and lung) We used microarrays to validate the Brain results of RNAse...
ORGANISM(S): Mus musculus 
2013-05-01 | GSE44555 | GEO
TranscriptomicsLiver expression data from four mouse strains treated with vehicle or PF-04287881 for seven days
PF-04287881 induced varying degrees of liver necrosis and phospholipidosis in a 34-inbred strain Mouse Diversity Panel (MDP) study. Four strains with differing susceptibilities to these phenotypes (MA/MyJ, NZW/LacJ, SM/J, WSB/EiJ) were selected for analysis of gene expression changes in the liver. T...
ORGANISM(S): Mus musculus 
2016-10-21 | E-GEOD-52620 | biostudies-arrayexpress
UnknownAntiangiogenic activity of phthalides-enriched Angelica Sinensis extract by suppressing WSB-1/pVHL/HIF-1α/VEGF signaling in bladder cancer.
Not available
S-EPMC5511260 | biostudies-literature
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