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TranscriptomicsPatterns of dioxin-altered mRNA expression in livers of dioxin-sensitive versus dioxin-resistant rats
The dioxin congener 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes a wide range of toxic effects in rodent species, all of which are mediated by a ligand-dependent transcription-factor, the aryl hydrocarbon receptor (AHR). The Han/Wistar (Kuopio) (H/W) strain shows exceptional resistance to many ...
ORGANISM(S): Rattus norvegicus 
2011-11-14 | E-GEOD-13513 | biostudies-arrayexpress
TranscriptomicsThe Aryl Hydrocarbon Receptor Regulates Tissue-Specific Dioxin-Dependent and Dioxin-Independent Gene Batteries: Liver
The aryl hydrocarbon receptor (AHR) is a widely-expressed ligand-dependent transcription-factor that mediates cellular responses to dioxins and other planar aromatic hydrocarbons. Indeed, AHR-null mice are refractory to the physiological effects of dioxin-exposure. Although some mechanistic aspects ...
ORGANISM(S): Mus musculus 
2009-09-21 | E-GEOD-15858 | biostudies-arrayexpress
TranscriptomicsThe Aryl Hydrocarbon Receptor Regulates Tissue-Specific Dioxin-Dependent and Dioxin-Independent Gene Batteries: Kidney
The aryl hydrocarbon receptor (AHR) is a widely-expressed ligand-dependent transcription-factor that mediates cellular responses to dioxins and other planar aromatic hydrocarbons. Indeed, AHR-null mice are refractory to the physiological effects of dioxin-exposure. Although some mechanistic aspects ...
ORGANISM(S): Mus musculus 
2009-09-21 | E-GEOD-15857 | biostudies-arrayexpress
TranscriptomicsThe Aryl Hydrocarbon Receptor Regulates Tissue-Specific Dioxin-Dependent and Dioxin-Independent Gene Batteries
This SuperSeries is composed of the following subset Series: GSE15857: The Aryl Hydrocarbon Receptor Regulates Tissue-Specific Dioxin-Dependent and Dioxin-Independent Gene Batteries: Kidney GSE15858: The Aryl Hydrocarbon Receptor Regulates Tissue-Specific Dioxin-Dependent and Dioxin-Independent Gene...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-15859 | biostudies-arrayexpress
TranscriptomicsNanoString analysis of a rat liver mRNA panel following TCDD treatment
Profiling of mRNA abundances with high-throughput platforms such as microarrays and RNA-Seq has become an important tool in both basic and biomedical research. However these platforms remain prone to systematic errors, and have challenges in clinical and industrial application. As a result it is sta...
ORGANISM(S): Rattus norvegicus 
2013-12-31 | E-GEOD-43251 | biostudies-arrayexpress
TranscriptomicsA Role for the RNA-Binding Protein MOS2 in MicroRNA Maturation in Arabidopsis
microRNAs (miRNAs) play important roles in the regulation of gene expression. In Arabidopsis, mature miRNAs are processed from primary miRNA transcripts (pri-miRNAs) by nuclear HYL1/SE/DCL1 complexes that form Dicing bodies (D-bodies). Here we report that a RNA-binding protein MOS2 bound to pri-miRN...
ORGANISM(S): Arabidopsis thaliana 
2012-10-27 | E-GEOD-41843 | biostudies-arrayexpress
UnknownSulfonate N-Heterocyclic Carbene-Copper Complexes: Uniquely Effective Catalysts for Enantioselective Synthesis of C-C, C-B, C-H, and C-Si Bonds.
Not available
S-EPMC7609658 | biostudies-literature
UnknownAcoustic hologram-induced virtual in vivo enhanced waveguide (AH-VIEW).
Not available
S-EPMC11811914 | biostudies-literature
UnknownHypoglycemia unawareness identified by continuous glucose monitoring system is frequent in outpatients with type 2 diabetes without receiving intensive therapeutic interventions.
Not available
S-EPMC9703673 | biostudies-literature
TranscriptomicsRetinoid X Receptor activation reverses the age-related deficiency in myelin debris phagocytosis and enhances remyelination
The efficiency of central nervous system (CNS) remyelination declines with age. This is in part due to an age-associated decline in the phagocytic removal of myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation. In this study we show that expression of genes i...
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-66988 | biostudies-arrayexpress
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