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GenomicsscONE-seq: A one-tube single-cell multi-omics method enables simultaneous dissection of genotype and phenotype heterogeneity from frozen tumor samples
scONE-seq: A one-tube single-cell multi-omics method enables simultaneous dissection of genotype and phenotype heterogeneity from frozen tumor samples
PRJNA768428 | ENA
GenomicsCharacterizing resistant cellular states in nasopharyngeal carcinoma during EBV lytic induction
Characterizing resistant cellular states in nasopharyngeal carcinoma during EBV lytic induction
PRJNA1108257 | ENA
TranscriptomicsQuantitative assessment of single-cell RNA sequencing methods
We generated single-cell transcriptomes from a large number of single cells using several commercially available platforms, in both microliter and nanoliter volumes, and compared performance between them. We benchmarked each method to conventional RNA-seq of the same sample using bulk total RNA, as ...
ORGANISM(S): Homo sapiens 
2013-10-20 | E-GEOD-51254 | biostudies-arrayexpress
UnknownPOEMS syndrome in the 21st century: A bibliometric analysis.
Not available
S-EPMC10570589 | biostudies-literature
UnknownCharacterization, Genomic Organization, Abundance, and Chromosomal Distribution of Ty1-copia Retrotransposons in Erianthus arundinaceus.
Not available
S-EPMC5461294 | biostudies-literature
TranscriptomicsHigh-throughput phenotyping of lung cancer somatic mutations [main experiment]
Recent genome sequencing efforts have identified millions of somatic mutations in cancer. However, the functional impact of most variants is poorly understood. Here we characterize 194 somatic mutations identified in primary lung adenocarcinomas using L1000 high-throughput gene-expression assays fol...
ORGANISM(S): Homo sapiens 
2016-06-28 | E-GEOD-83744 | biostudies-arrayexpress
UnknownStructural transition of parenthood among Chinese nulliparous couples with planned pregnancies, 2013-2019.
Not available
S-EPMC10696718 | biostudies-literature
ProteomicsMouse kidney and cell lines LC-MS/MS
Zinc (Zn) is an essential micronutrient and cofactor for up to 10% of proteins in living organisms. During Zn limitation, specialized enzymes called metallochaperones are predicted to allocate Zn to specific metalloproteins. This function has been putatively assigned to G3E GTPase COG0523 proteins,...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD031516 | Pride
Mouse Targeteed Shotgun Zinc 
TranscriptomicsDynamic Chromatin Localization of Sirt6 Shapes Stress- and Aging- Related Transcriptional Networks (Illumina)
Sirtuins (Sirt) are a family of enzymes that modify chromatin and other proteins to affect gene activity. Loss of Sirt6 leads to a progeria-like phenotype in mice, but the target of SIRT6 action has been elusive. Here we show that Sirt6 binds to thousands of gene promoters in a stress-inducible fash...
ORGANISM(S): Mus musculus 
2011-05-11 | E-GEOD-28585 | biostudies-arrayexpress
TranscriptomicsDynamic Chromatin Localization of Sirt6 Shapes Stress- and Aging- Related Transcriptional Networks (ChIP-chip)
Sirtuins (Sirt) are a family of enzymes that modify chromatin and other proteins to affect gene activity. Loss of Sirt6 leads to a progeria-like phenotype in mice, but the target of SIRT6 action has been elusive. Here we show that Sirt6 binds to thousands of gene promoters in a stress-inducible fash...
ORGANISM(S): Mus musculus 
2011-05-11 | E-GEOD-28638 | biostudies-arrayexpress
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