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MetabolomicsDysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multi-drug resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to control infection including zinc stres...

2022-02-23 | MTBLS318 | MetaboLights
MetabolomicsZinc oxide nanoparticles supplementation improve the quality and lipid profiles of boar frozen semen

Oxidative stress frequently causes a reduction in the quality of frozen-thawed sperm. Zinc oxide nanoparticles (ZnONPs) has an antioxidant protective effect on frozen semen of animals such as goats, camels and buffaloes. However, it is not clear whether ZnONPs can improve the quality and lipid co...

2026-05-05 | MTBLS12892 | MetaboLights
MetabolomicsAssessment of dietary zinc on SCFA cecal production
Not available
ORGANISM(S): Gallus gallus 
ST000190 | MetabolomicsWorkbench
MetabolomicsDisruption of Zinc homeostasis can impair maternal glucocorticoid metabolism: consequences on the developing fetus
Not available
ORGANISM(S): Rattus norvegicus 
ST000120 | MetabolomicsWorkbench
TranscriptomicsThe effect of zinc limitation on transcriptome expression in Pseudomonas fluorescens Pf-5
Transcriptomic profiling of Pseudomonas fluorescens Pf-5 comparing zinc-limited culture against zinc-amended culture in M9 minimal media Two-condition experiment, non-zinc treated culture versus zinc sulphate supplemented culture. 3 biological replicates including 3 technical replicates for one of t...
ORGANISM(S): Pseudomonas fluorescens 
2011-10-12 | E-GEOD-32921 | biostudies-arrayexpress
MetabolomicsEffects of Zinc on GI tract metabolites (Part 2: Prostate)
Not available
ORGANISM(S): Mus musculus 
ST000331 | MetabolomicsWorkbench
MetabolomicsEffects of Zinc on GI tract metabolites (Part 1: Esophagus)
Not available
ORGANISM(S): Mus musculus 
ST000330 | MetabolomicsWorkbench
TranscriptomicsZinc-dependent regulation of the adh1 antisense transcript in fission yeast
In yeast, alcohol dehydrogenase I (Adh1) is an abundant zinc binding protein that is required for the conversion of acetaldehyde to ethanol. Through transcriptome profiling of the Schizosaccharomyces pombe genome, we identified a natural antisense transcript at the adh1 locus that is induced in resp...
ORGANISM(S): Schizosaccharomyces pombe 
2012-12-12 | E-GEOD-39701 | biostudies-arrayexpress
ProteomicsA conserved nucleotide-dependent metal chaperone for managing the cellular zinc economy during zinc limitation
How cells safeguard essential zinc-dependent functions during zinc deficiency is poorly understood. A long-debated strategy is whether soluble metal-trafficking chaperones exist to prioritize specific zinc-dependent proteins. We identified a eukaryotic family of metallochaperones that physically int...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
MSV000088135 | MassIVE
TranscriptomicsDynamic transcriptomic profiles of zebrafish gills in response to zinc supplementation.
Dietary zinc is routinely supplemented to promote growth, boost the immune system, protect against diabetes or aid recovery from diarrhoea. We exploited the zebrafish (Danio rerio) gill as a unique vertebrate ion transporting epithelium model to study the time-dependent regulatory networks of gene-e...
ORGANISM(S): Danio rerio 
2010-05-20 | E-GEOD-21907 | biostudies-arrayexpress
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