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ProteomicsLabel-free proteome analysis of small extracellular vesicles (sEV) expressing different HRS mutants.
Label-free proteome analysis of small extracellular vesicles (sEV) derived from WM9 cells expressing different HRS mutants: wild type (HRSWT), phospho-deficient (HRSS345A), and phospho-mimetic mutant HRS (HRSS345D).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-02-16 | MSV000088846 | MassIVE
TranscriptomicsType 1 interferons induce changes in core metabolism that are critical for immune function
Type 1 interferons (IFNs) induce complex responses that can be beneficial or deleterious, depending on context. Greater understanding of the mechanisms of action of these cytokines could allow new therapeutic approaches. We found that type 1 IFNs induced changes in cellular metabolism that were cr...
ORGANISM(S): Mus musculus 
2016-07-01 | E-GEOD-81889 | biostudies-arrayexpress
TranscriptomicsInfluence of 17M-NM-2-estradiol on Gene Expression of Paracoccidioides During Mycelia-to-Yeast Transition
Background: Paracoccidioides is the causative agent of paracoccidioidomycosis, a systemic mycosis endemic to Latin America. Infection is initiated by inhalation of conidia (C) or mycelial (M) fragments, which subsequently differentiate into yeast (Y). Epidemiological studies show a striking predomin...
ORGANISM(S): Paracoccidioides brasiliensis Pb01 
2011-12-14 | E-GEOD-30466 | biostudies-arrayexpress
TranscriptomicsThe genetic landscape of mutations in Burkitt lymphoma
Burkitt lymphoma is characterized by deregulation of MYC, but the contribution of other genetic mutations to the disease is largely unknown. Here, we describe the first completely sequenced genome from a Burkitt lymphoma tumor and germline DNA from the same affected individual. We further sequen...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-48435 | biostudies-arrayexpress
UnknownTherapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
Not available
S-EPMC4962737 | biostudies-literature
TranscriptomicsTranscription profiling of mouse small intestine from PlagL2-/- animals reveals transcription factor PlagL2 regulates steps in chylomicron metabolism
Enterocytes assemble dietary lipids into chylomicron particles that are taken up by intestinal lacteal vessels and peripheral tissues. Although chylomicrons are known to assemble in part within membrane secretory pathways, the modifications required for efficient vascular uptake are unknown. We repo...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9123 | biostudies-arrayexpress
UnknownCytogenetic prognostication within medulloblastoma subgroups.
Not available
S-EPMC3948094 | biostudies-literature
UnknownCardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair.
Not available
S-EPMC8759793 | biostudies-literature
TranscriptomicsPro-invasion metastasis drivers in early stage melanoma are oncogenes
Clinical and genomic evidence support the view that the metastatic potential of a primary tumor may be dictated by transforming events acquired early in the tumorigenic process. It has been proposed that the presence of such pro-metastatic events in early-stage tumors reflects their additional capa...
ORGANISM(S): Mus musculus 
2011-07-11 | E-GEOD-29074 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human breast cancer cell line MCF7, T47D and CAMA-1 treated that are naïve and resistant to capivasertib and have been treated with acute capivasertib, continuous capivasertib and DMSO
MCF7, T47D and CAMA-1 cell lines were treated with long-term (continuous) capivasertib to induce resistant cell-lines (T47D P1, MCF7 P1 and CAMA-1 P1). The naïve (or parental) cell lines had RNAseq sequencing at treatment with DMSO and treatment with capivasertib. Resistant cell lines had RNAseq seq...
ORGANISM(S): Homo sapiens 
2026-05-25 | E-MTAB-16414 | biostudies-arrayexpress
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