Sort   by:  
 Page size 
UnknownExpression profiles and polymorphic identification of the ACSL1 gene and their association with body size traits in Dezhou donkeys.
Finding out the genetic mechanism of growth and development traits and the development of related molecular markers can help improve the breeding of livestock. The long-chain acyl coenzyme A synthase 1 (ACSL1) gene plays a major role in lipid synthesis and fatty acid catabolism. However, ther...
S-EPMC7810223 | biostudies-literature
UnknownClinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.

Background

Developmental disorders (DDs) are early onset disorders affecting 5%-10% of children worldwide. Chromosomal microarray analysis detecting CNVs is currently recommended as the first-tier test for DD diagnosis. However, this analysis omits a high percentage of disease-causing single...
S-EPMC7418612 | biostudies-literature
UnknownComparison of anti-thymocyte globulin-based immunosuppressive therapy and allogeneic hematopoietic stem cell transplantation in patients with transfusion-dependent non-severe aplastic anaemia: a retrospective study from a single centre.

Objectives

The selection and timing of anti-thymocyte globulin (ATG)-based immunosuppressive therapy (IST) or allogeneic hematopoietic stem cell transplantation (allo-HSCT) in patients with transfusion-dependent non-severe aplastic anemia (TD-NSAA) pose significant clinical challenges. This ...
S-EPMC10595398 | biostudies-literature
UnknownStructural Characterization of the N-Terminal Domain of the Dictyostelium discoideum Mitochondrial Calcium Uniporter.
The mitochondrial calcium uniporter (MCU) plays a critical role in mitochondrial calcium uptake into the matrix. In metazoans, the uniporter is a tightly regulated multicomponent system, including the pore-forming subunit MCU and several regulators (MICU1, MICU2, and Essential MCU REgulator, EMRE). ...
S-EPMC7114133 | biostudies-literature
UnknownCombined lung and diaphragm ultrasound predicts extubation outcomes in ARDS: a prospective study.

Background

Extubation failure is a crucial issue for acute respiratory distress syndrome (ARDS). Ultrasound of the lung and diaphragm is individually valuable for predicting extubation outcomes. We aimed to determine whether combined lung and diaphragmatic ultrasound could improve the accura...
S-EPMC11495000 | biostudies-literature
UnknownPositively selected genes of the Chinese tree shrew (Tupaia belangeri chinensis) locomotion system.
While the recent release of the Chinese tree shrew (Tupaia belangeri chinensis) genome has made the tree shrew an increasingly viable experimental animal model for biomedical research, further study of the genome may facilitate new insights into the applicability of this model. For example, though t...
S-EPMC5055547 | biostudies-literature
UnknownStudy of the doubly charmed tetraquark [Formula: see text].
Quantum chromodynamics, the theory of the strong force, describes interactions of coloured quarks and gluons and the formation of hadronic matter. Conventional hadronic matter consists of baryons and mesons made of three quarks and quark-antiquark pairs, respectively. Particles with an alternative q...
S-EPMC9203551 | biostudies-literature
UnknownOutbreak of febrile illness caused by coxsackievirus A4 in a nursery school in Beijing, China.

Background

Coxsackievirus A4 (CV-A4) is classified as human enterovirus A according to its serotype. CV-A4, an etiological agent of hand, foot, and mouth disease, affects children worldwide and can circulate in closed environments such as schools and hospitals for long periods.

Findings

S-EPMC4495935 | biostudies-literature
UnknownLate miocene-pliocene paleoclimatic evolution documented by terrestrial mollusk populations in the western Chinese Loess Plateau.
The Neogene eolian deposits in the Chinese Loess Plateau (CLP) are one of the most useful continental deposits for understanding climatic changes. To decipher Late Neogene paleoclimatic changes in the CLP, we present a terrestrial mollusk record spanning the time interval between 7.1 and 3.5 Ma from...
S-EPMC3994151 | biostudies-literature
ProteomicsComparison of the proteome-wide alkylation signatures of antimalarial peroxides: ozonides vs. artemisinin
Antimalarial peroxides such as the phytochemical artemisinin or the synthetic artefenomel are activated by reductive cleavage of the peroxide bond. This happens inside the malaria parasite, presumably in the food vacuole with ferrous heme as the electron donor. The generated carbon-centered radicals...
ORGANISM(S): Plasmodium falciparum NF135/5.C10 
2022-02-24 | PXD010264 | Pride
Malaria Label-free quantification Peroxides 
Sort   by:  
 Page size