Sort   by:  
 Page size 
TranscriptomicsGenome-wide Regulation of 5hmC, 5mC and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells (ChIP-seq data)
DNA methylation of C5-cytosine (5mC) in the mammalian genome is a key epigenetic event that is critical for various cellular processes. However, how the genome-wide 5mC pattern is dynamically regulated remains a fundamental question in epigenetic biology. The TET family of 5mC hydroxylases, which co...
ORGANISM(S): Mus musculus 
2011-04-21 | E-GEOD-28532 | biostudies-arrayexpress
GenomicsLoss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
DNA methylation at the 5-position of cytosine (5-mC) is a key epigenetic mark critical for varius biological and pathological processes. 5-mC can be converted to 5-hydroxymethylcytosine (5-hmC) by the Ten-Eleven Translocation (TET) family of DNA hydroxylases. Here we report that "loss of 5-hmC&...
ORGANISM(S): Homo sapiens 
2012-09-18 | E-GEOD-38231 | biostudies-arrayexpress
GenomicsGenome-wide Regulation of 5hmC, 5mC and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells (bisulfite sequencing data)
DNA methylation of C5-cytosine (5mC) in the mammalian genome is a key epigenetic event that is critical for various cellular processes. However, how the genome-wide 5mC pattern is dynamically regulated remains a fundamental question in epigenetic biology. The TET family of 5mC hydroxylases, which co...
ORGANISM(S): Mus musculus 
2011-04-21 | E-GEOD-28533 | biostudies-arrayexpress
TranscriptomicsPHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression
Histone methylation occurs on both lysine and arginine residues and its dynamic regulation plays a critical role in chromatin biology. Here we identify the UHRF1 PHD domain (PHDUHRF1), an important regulator of DNA CpG methylation, as an unanticipated histone H3 unmodified arginine 2 (H3R2)-recognit...
ORGANISM(S): Homo sapiens 
2011-07-07 | E-GEOD-30478 | biostudies-arrayexpress
ProteomicsRACK7 Senses and Fine-Tunes Enhancer Activity
RACK7 senses enhancer activity changes and facilitates their activation
ORGANISM(S): Homo Sapiens 
2025-05-26 | PXD058592 |
ProteomicsQuantitative acetylome analysis reveals histone modifications that may predict prognosis in hepatitis B-related hepatocellular carcinoma
Lysine acetylation (Kac) as an important post-translational modification of histone is essential for gene expression regulation in hepatocellular carcinoma (HCC), however the atlas of whole acetylated proteins for HCC tissue and the difference of protein acetylation between human normal and HCC tiss...
ORGANISM(S): Homo Sapiens 
2020-10-24 | PXD022161 |
Sort   by:  
 Page size