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ProteomicsPulmonary microvascular endothelial cells support alveolar epithelial growth via bone morphogenetic protein 6 secretion
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation and emphysema development, associated with enhanced tissue destruction and defective repair. Supporting cells in the alveolar niche play a crucial role in guiding the activation of alveolar epithelial pro...
ORGANISM(S): Homo sapiens (Human) 
2026-07-02 | PXD053755 | Pride
Bmp6 Pulmonary microvascular endothelial cells Copd 
TranscriptomicsTranscription profiling of livers from mice overexpress ABCA1 in LDL receptor -/- genetic background to characterize the effects of ABCA1 overexpression.
Changes in the transcript profile due to ABCA1 expression in murine liver samples was evaluated in LDL receptor -/- genetic backgrounds. Experiment Overall Design: Case (ABCA1-transgenic) versus control (wild-type) design with 4 biological replicates per condition
ORGANISM(S): Mus musculus 
2007-11-13 | E-GEOD-5496 | biostudies-arrayexpress
GenomicsThe genomic complexity of sporadic and inherited retinoblastoma with a matched orthotopic xenograft

Retinoblastoma is a pediatric cancer of the developing retina. All retinoblastomas are believed to initiate with biallelic inactivation of the RB1 gene. To identify subsequent genetic lesions in retinoblastoma, we performed whole genome sequencing of tumor and normal DNA of 4 children with retino...

phs000352.v1.p1 | EGA
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