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ProteomicsDrug sensitivity, gene dependency and proteogenomic correlates of the spectrum of telomere maintenance mechanisms in cancer cells
Replicative immortality is a hallmark of cancer, driven by activation of telomere maintenance mechanisms (TMM), that is yet to be therapeutically exploited. To expedite discoveries that will enable development of TMM-targeted therapeutics, we have generated a resource of telomere biology metrics for...
ORGANISM(S): Homo sapiens (Human) 
2025-10-17 | PXD058664 | Pride
Tmm Cancer Proteomics Swath-dia Telomere biology 
TranscriptomicsThe genetic landscape of mutations in Burkitt lymphoma
Burkitt lymphoma is characterized by deregulation of MYC, but the contribution of other genetic mutations to the disease is largely unknown. Here, we describe the first completely sequenced genome from a Burkitt lymphoma tumor and germline DNA from the same affected individual. We further sequen...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-48435 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-IBIOS-07-04-2017-10:40:02:500-10 - samples
RNA sequencing data for 170 medulloblastoma tumor samples
EGAD00001003279 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-03-01-2017-12:51:29:816-785 - samples
WGS data of medulloblastoma tumor/control pairs.
EGAD00001003127 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-03-01-2017-12:19:28:146-782 - samples
WGS data of medulloblastoma tumor/control pairs.
EGAD00001003126 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-03-01-2017-12:02:16:545-781 - samples
WGS data of medulloblastoma tumor/control pairs.
EGAD00001003125 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-03-01-2017-12:56:49:446-789 - samples
Exome sequencing data for medulloblastoma tumor/control pairs
EGAD00001003128 | EGA
GenomicsMedulloblastoma expression profiling (mbt)
Medulloblastoma expression profiling
EGAD00010001300 | EGA
GenomicsComprehensive molecular profiling identifies novel genetic drivers and subtypes underlying medulloblastoma
Current therapies for medulloblastoma (MB), a highly malignant childhood brain tumor, impose debilitating effects on the developing child, warranting the development of molecularly targeted treatments with reduced toxicities. Prior studies have failed to disclose the full spectrum of driver genes an...
EGAS00001001953 | EGA
GenomicsSTJUDE_450k
Medulloblastoma methylation profiling
EGAD00010001319 | EGA
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