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TranscriptomicsTranscription profiling by array of acute myeloid leukemia patient samples for analysis of KIT and SP1 expression
Oligonucleotide expression microarray data used for analysis of KIT and SP1 expression levels in AML patient samples
ORGANISM(S): Homo sapiens 
2011-03-16 | E-TABM-945 | biostudies-arrayexpress
Transcriptomicsinv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations
The inv(16)(p13q22)/t(16;16)(p13;q22) in acute myeloid leukemia results in multiple CBFB-MYH11 fusion transcripts, with type A being most frequent. The biologic and prognostic implications of different fusions are unclear. We analyzed CBFB-MYH11 fusion types in 208 inv(16)/t(16;16) patients with de ...
ORGANISM(S): Homo sapiens 
2013-01-23 | E-MTAB-1356 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Nipponbare rice roots over a time course of potassium deprivation
Potassium (K+) is one of the most important nutrient ions in plant cells and play crucial roles in many plant physiological and developmental processes. K+ deficiency is the common abiotic stress in natural environment, which inhibits plant growth and reduces production of crops. We used microarrays...
ORGANISM(S): Oryza sativa japonica 
2012-10-31 | E-GEOD-37161 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of novel antigen presenting cells (APC) inducing pathogenic T helper cells of lupus
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-36284 | biostudies-arrayexpress
UnknownA skin in situ immune cell detection kit for the diagnosis and classification of cutaneous lupus erythematosus.
Not available
S-EPMC8339827 | biostudies-literature
UnknownSp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia.
Not available
S-EPMC2917066 | biostudies-literature
TranscriptomicsPten loss and RAS/MAPK activation cooperate to promote EMT and prostate cancer metastasis initiated from stem/progenitor cells
PTEN loss or PI3K/AKT signaling pathway activation correlates with human prostate cancer progression and metastasis. However, in preclinical murine models, deletion of Pten alone fails to mimic the significant metastatic burden that frequently accompanies the end stage of human disease. To identify...
ORGANISM(S): Mus musculus 
2012-02-28 | E-GEOD-34839 | biostudies-arrayexpress
UnknownDesign and pharmacology of a highly specific dual FMS and KIT kinase inhibitor.
Not available
S-EPMC3619323 | biostudies-literature
UnknownHuman KIT+ myeloid cells facilitate visceral metastasis by melanoma.
Not available
S-EPMC8056753 | biostudies-literature
UnknownNintedanib overcomes drug resistance from upregulation of FGFR signalling and imatinib-induced KIT mutations in gastrointestinal stromal tumours.
Not available
S-EPMC9019892 | biostudies-literature
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