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TranscriptomicsQuality control of spliced mRNAs requires the shuttling SR-proteins Gbp2 and Hrb1
Eukaryotic cells have to prevent the export of unspliced pre-mRNAs until intron removal is completed to avoid the expression of aberrant and potentially harmful proteins. Only mature RNAs associate with the export receptor Mex67 (mammalian TAP) and enter the cytoplasm. The underlying nuclear quality...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-04 | E-GEOD-52808 | biostudies-arrayexpress
TranscriptomicsThe shuttling SR-like proteins Gbp2 and Hrb1 mediate the nuclear export of spliced mRNAs
Three shuttling SR-like proteins exist in Saccharomyces cerevisiae, Npl3, Gbp2 and Hrb1, that are involved in the nuclear export of mRNAs. In a screen for genes that regulate the export of Gbp2, we identified novel mutants of the splicing factors PRP8 and PRP17 that lead to severe mislocalization de...
ORGANISM(S): Saccharomyces cerevisiae 
2013-08-30 | E-GEOD-20738 | biostudies-arrayexpress
UnknownResveratrol prevents gallstones in mice fed on a high fat diet via regulating PPAR-γ and SR-BI.
Not available
S-EPMC11955665 | biostudies-literature
UnknownLarge-scale multicenter study reveals anticitrullinated SR-A peptide antibody as a biomarker and exacerbator for rheumatoid arthritis.
Not available
S-EPMC11698088 | biostudies-literature
TranscriptomicsTemporal effects of intermittent- and sustained hypoxia on gene expression patterns in rat lungs
Time-course gene expression profiles were obtained from lung tissues of the rats treated with room air, intermittent- (IH) or sustained hypoxia (SH) for 1, 3, 7, 14 and 30 days using CodeLink microarrays. Using a systems biology approach, we observed that two different mechanisms are involved in the...
ORGANISM(S): Rattus norvegicus 
2008-12-17 | E-GEOD-8705 | biostudies-arrayexpress
ProteomicsCell-Surface Proteomic Profiling in the Fly Brain Uncovers New Wiring Regulators
Li J, Han S, Li H, Udeshi ND, Svinkina T, Mani DR, Xu C, Guajardo R, Xie Q, Li T, Luginbuhl DJ, Wu B, McLaughlin CN, Xie A, Kaewsapsak P, Quake sR, Carr SA, Ting AY, Luo L. 2019. Molecular interactions at the cellular interface mediate organized assembly of single cells into tissues, and thus govern...
ORGANISM(S): Drosophila <fruit Fly, Genus> (ncbitaxon:7215) 
2019-11-06 | MSV000084543 | MassIVE
TranscriptomicsmRNA-seq data of 14 days old Arabidopsis seedlings in Col-0 and At rz-1b At rz-1c double mutant
Nuclear-localized RNA binding proteins are involved in various aspects of RNA metabolism, which in turn modulates gene expression. However, the functions of nuclear-localized RNA binding proteins in plants are poorly understood. Here we report the functions of two proteins containing RNA recognition...
ORGANISM(S): Arabidopsis thaliana 
2015-12-15 | E-GEOD-75959 | biostudies-arrayexpress
UnknownRetinal microvasculature alteration in patients with systemic sclerosis and chloroquine treatment.
Not available
S-EPMC9511431 | biostudies-literature
UnknownSublethal irradiation promotes the metastatic potential of hepatocellular carcinoma cells.
Not available
S-EPMC7780048 | biostudies-literature
UnknownTranscutaneous auricular vagal nerve stimulation for consciousness recovery in patients with prolonged disorders of consciousness (TAVREC): study protocol for a multicenter, triple-blind, randomized controlled trial in China.
Not available
S-EPMC11149147 | biostudies-literature
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