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ProteomicsSIRT2 regulates extracellular vesicle-mediated liver-bone communication
The interplay between liver and bone metabolism remains largely uncharacterized. Here, we uncover a mechanism of liver-bone crosstalk regulated by hepatocyte SIRT2. We demonstrate that hepatocyte SIRT2 expression is increased in aged mice and elderly humans. Liver-specific SIRT2 deficiency inhibits ...
ORGANISM(S): Mus Musculus 
2023-03-27 | PXD041145 |
ProteomicsCBX4 contributes to HIV-1 latency by forming phase-separated nuclear bodies and SUMOylating EZH2
Molecular mechanisms of HIV-1 latency have been studied extensively to achieve a functional cure for the acquired immunodeficiency syndrome (AIDS). To develop more promising latency-reversing agents (LRAs) to efficiently reactivate the latent reservoir which is subsequently eliminated by immune surv...
ORGANISM(S): Homo Sapiens 
2022-01-14 | PXD031011 |
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
Not available
S-EPMC9259496 | biostudies-literature
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