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ProteomicsBranched-K29/K48 and K48/K29 polyUb_LC-MSMS
The E3 ubiquitin ligase Ufd4/TRIP12 and the E4 enzyme Ufd2 are capable of catalyzing branched ubiquitination. Here, we employ LC-MS/MS to characterize the specific ubiquitin linkage types involved in these branched ubiquitin chains.
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2025-04-10 | PXD062799 | Pride
Branched ubiquitin chain lc-msms 
UnknownSlightly Li-enriched chemistry enabling super stable LiNi0.5Mn0.5O2 cathodes under extreme conditions.
Not available
S-EPMC11331316 | biostudies-literature
UnknownImpact of transapical beating-heart septal myectomy on left atrial remodeling and atrioventricular coupling in hypertrophic obstructive cardiomyopathy.
Not available
S-EPMC12182824 | biostudies-literature
ProteomicsSequential release of interacting proteins and Ub-modifying enzymes by disulfide heterotypic ubiquitin reagents
Heterotypic ubiquitin (Ub) chains have emerged as fundamental components in a wide range of cellular processes. The integrative identification of Ub-interacting proteins (readers) and Ub-modifying enzymes (writers and erasers) that selectively recognize and regulate heterotypic ubiquitination may pr...
ORGANISM(S): Saccharomyces Cerevisiae 
2023-09-28 | PXD045936 |
UnknownHeterogeneous clinical and functional features of GRIN2D-related developmental and epileptic encephalopathy.
Not available
S-EPMC6763743 | biostudies-literature
ProteomicsSynthetic lethal combinations targeting PLK1-CBX8-GPX4 axis with BRAF and EGFR inhibition in BRAF V600E colorectal cancer
Metastatic BRAFV600E colorectal cancer (CRC) confers poor prognosis and run into a bottleneck in the current treatment strategies. To identify regulatory pathways independent of the MAPK pathway in BRAFV600E CRC, we performed CRISPR-Cas9 screening, and and find targeting glutathione peroxidase 4 (GP...
ORGANISM(S): Homo Sapiens 
2024-11-25 | PXD058213 |
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