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ProteomicsIntegrated Proteogenomic Characterization of Localized Prostate Cancer Identifies Biological Insights and Subtype-Specific Therapeutic Strategies
We profiled the genome, transcriptome, proteome and phosphoproteome of 145 cases of localized prostate cancer (PCa) in Chinese patients and revealed three subtypes with distinct molecular features. We integrated multi-omic data to refine molecular subtyping of localized PCa, and identified NANS as a...
ORGANISM(S): Homo Sapiens 
PXD056748 |
ProteomicsProteomics of prostate cancer orthotopic transplanted mice
We profiled the proteomics of prostate cancer orthotopic transplanted mice.
ORGANISM(S): Mus Musculus 
2025-01-21 | PXD058636 |
ProteomicsProteomics of prostate cancer cell lines
We profiled the proteomics of prostate cancer (PCa) cell lines.
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-12-06 | PXD058635 |
UnknownComparison of RNA-seq and microarray-based models for clinical endpoint prediction.

Background

Gene expression profiling is being widely applied in cancer research to identify biomarkers for clinical endpoint prediction. Since RNA-seq provides a powerful tool for transcriptome-based applications beyond the limitations of microarrays, we sought to systematically evaluate the...
S-EPMC4506430 | biostudies-literature
UnknownA comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium.
We present primary results from the Sequencing Quality Control (SEQC) project, coordinated by the US Food and Drug Administration. Examining Illumina HiSeq, Life Technologies SOLiD and Roche 454 platforms at multiple laboratory sites using reference RNA samples with built-in controls, we assess RNA ...
S-EPMC4321899 | biostudies-literature
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