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TranscriptomicsRNA-seq data in cardiac tissues from cardiomyocyte-specific Acsl4 knockout mice after transverse aortic constriction
In order to investigate the differentially expressed genes in Acsl4 knockout after TAC (Transverse aortic constriction) or sham surgery. The experiment was divided to four groups including sham-operated Acsl4 flox/flox mice (FS), sham-operated Acsl4 knockout mice (KS), TAC-operated Acsl4 flox/flox m...
ORGANISM(S): Mus musculus 
2024-08-26 | E-MTAB-14383 | biostudies-arrayexpress
ProteomicsQuantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting PDGFRβ/PI3K/AKT pathway
Yinchenzhufu decoction (YCZFD) is a traditional Chinese medicine formula with hepatoprotective effects. In this study, the protective effects of YCZFD against cholestatic liver fibrosis and its mechanisms of action were evaluated in a mouse model of 3,5-diethoxycarbonyl-1,4-dihydro-collidine (DDC)-i...
ORGANISM(S): Mus Musculus 
2023-10-13 | PXD046101 |
ProteomicsFOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer
The forkhead protein FOXA1 has been found to play a critical role in orchestrating hormonal-signaling network and to function as a pioneer factor to regulate breast-specific gene expression,However, whether interplay between O-GlcNAcylation and FOXA1 affects the genome-wide transcriptional activity ...
ORGANISM(S): Homo Sapiens 
2022-12-21 | PXD039019 |
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