Wu Zhenghua Z - OmicsDI

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Proteomics (3)
Metabolomics (1)

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Mus musculus (2)
Camellia sinensis (1)

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iProX (3)
MetaboLights (1)

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Mass spectrometry (1)

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Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - negative - reverse phase (1)

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2025 (3)
2024 (1)

Metabolite Name

Nicotinamide n-oxide (1)
Dl-3-aminoisobutyric acid (1)
Bata-carotene (1)
14,15-epoxy-5z,8z,11z-eicosatrienoic acid (1)
1,2-distearoyl-sn-glycero-3-phosphocholine (1)
.beta.-damascone (1)
P-tolyl-.beta.-d-glucuronide (1)
S-adenosyl-l-methionine (1)
Palmitoyl coa (1)
8s-hydroxy-5z,9e,11z,14z-eicosatetraenoic acid (1)
5,6-dihydroxyindole-2-carboxylic acid (1)
2-benzothiazole (1)
Glutamyl-s-methylcysteine (1)
12-oxo-5z,8z,10e,14z-eicosatetraenoic acid (1)
(+)-.alpha.-tocopherol (1)
Cis-10-heptadecenoic acid (1)
L-homocystine (1)
Pyrrol (1)
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-n,n-dimethyl (1)
1-lignoceroyl-2-hydroxy-sn-glycero-3-phosphocholine (1)
Protoporphyrin ix (1)
Prostaglandin b1 (1)
(+)-abscisic acid (1)
L-arabinose (1)
1,7-bis(4-hydroxyphenyl)heptan-3-one (1)
N-Acetyl-Asp-Glu (1)
Fenthion (1)
O-toluidine (1)
N-docosanoyl-4-sphingenyl-1-o-phosphorylcholine (1)
N-(eicosanoyl)sphingosine (1)

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UHPLC-Q-TOF MS-Based Serum Metabolomics Reveals the Therapeutic Effects of Berberine and Wumei Wan on APCmin/+ Mice

APCmin/+ mice (8-week-old) and wild-type C57BL/6 controls were divided into MOD (saline), BBR (100 mg/kg berberine), WMW (17 g/kg Wu Mei Wan), and CON (saline) groups. All mice received daily gavage for 10 weeks under a 60% high-fat diet. Serum samples were collected after euthanasia and subjecte...

2025-10-16 | MTBLS12598 | MetaboLights

Proteomics analysis of three tea cultivars

To decipher phenotypic differences in flavonoid metabolism and the abundance of UGT enzymes involved in flavonol glycoside biosynthesis, an integrated proteomics and metabolomics analysis was conducted on three tea cultivars (Camellia sinensis), namely Jinfenghuang, Fuyun 6 and Bantianyao.

ORGANISM(S): Camellia Sinensis

2024-01-30 | PXD048997 |

Si-pgc-1 α LNP prevents bladder cancer metastasis by inhibiting mitochondrial biogenesis and energy metabolism in cancer cells

This study aims to explore the effect of PGC-1 α siRNA delivered by liposomal nanoparticles on cancer cells through transcriptome, proteome and metabolome technologies, so as to reveal its regulatory effect on cancer cell reprogramming and energy metabolism, so as to provide clues for the molecular ...

ORGANISM(S): Mus Musculus

2025-03-22 | PXD062155 |

Targeting PGC-1α in Bladder Cancer: Unraveling Energy Metabolism Reprogramming for Therapeutic Intervention

Metastatic bladder cancer is a malignant tumor with high metastatic potential. The etiology and molecular mechanism are still not fully understood. This study aimed to investigate the effect of PGC-1 α siRNA delivered by liposomal nanoparticles on bladder cancer cells, in order to reveal its mechani...