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Proteomicsproteome sequencing for the colon tissues of mice with ckmt1 knockout
We here performed a proteomics study on the colon tissues of ckmt1 KOIEC or. WT (flox+/+) mice after DSS treatment for 8 days (n=3). KOIEC mice (Ckmt1flox/flox, Vil-Cre) means mice with intestinal epithelial conditional knockout (C57BL/6J). Cre-negative Ckmt1 flox/flox littermates were used as contr...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD057053 | Pride
Proteome sequencing  ibd  dss-induced model  mice  colon 
ProteomicsEnhancing Top-Down Proteomics Data Analysis by Combining Deconvolution Results through a Machine Learning Strategy
Top-down mass spectrometry (MS) is a powerful tool for identification and comprehensive characterization of proteoforms arising from alternative splicing, sequence variation, and post-translational modifications. While the technique is powerful, it suffered from the complex dataset generated from to...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2020-05-06 | PXD018043 | Pride
Top-down spectra deconvolution 
ProteomicsMASH Explorer: A Universal Software Environment for Top-Down Proteomics
MASH Explorer, a universal, comprehensive, and user-friendly software environment for top-down proteomics. MASH Explorer integrates multiple spectral deconvolution and database searching algorithms into a single, universal platform which can process top-down proteomics data from various vendor forma...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020615 | Pride
Top-down proteomics  data analysis software  proteoform characterization  intact protein analysis 
ProteomicsCoro1a promotes the multivesicular body and plasma membrane fusion by facilitating PKM2-mediated SNAP-23 phosphorylation
During the formation of endosomal pathway-dependent extracellular vesicles (EVs), intraluminal vesicles in multivesicular bodies (MVBs) fuse with the plasma membrane (PM), releasing intraluminal vesicles to produce exosomes. Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNAR...
ORGANISM(S): Homo Sapiens 
2025-12-07 | PXD071700 |
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