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TranscriptomicsInhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer
We analyzed transcriptional changes in 4 prostate cancer cell lines following treatment with the BET inhibitor I-BET762 using Affymetrix Human Genome U133 Plus 2.0 Arrays. Four prostate cancer cell lines (NCI-H660, VCaP, LNCaP, PC-3) were treated with DMSO (control) or I-BET762 at 0.5uM or 10uM con...
ORGANISM(S): Homo sapiens 
2014-03-31 | E-GEOD-56352 | biostudies-arrayexpress
TranscriptomicsGene expression study in Neuroblastoma after BET inhibition
We studied transcriptional changes by Illumina HumanHT-12 v4 microarrays in 2 Neuroblastoma cell lines after i-BET-726 treatment 2 neuroblastoma cell lines SK-N-SH and CHP-212 were treated with i-BET-726 at 100nM or 1uM concentrations for 16 hrs to study gene expression.
ORGANISM(S): Homo sapiens 
2013-08-23 | E-GEOD-47386 | biostudies-arrayexpress
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