Sort   by:  
 Page size 
TranscriptomicsRNA expression profiles in fibroblast-like synoviocytes from rheumatoid arthritis patients and trauma patients
LncRNA and mRNA microarrays were performed to identify differentially expressed lncRNAs and mRNAs in fibroblast-like synoviocytes from rheumatoid arthritis patients compared with fibroblast-like synoviocytes from trauma patients. Fibroblast-like synoviocytes were isolated from synovial tissues. LncR...
ORGANISM(S): Homo sapiens 
2016-06-10 | E-GEOD-83147 | biostudies-arrayexpress
TranscriptomicssiRNA Knockdown of SWI/SNF complex proteins in prostate cancer cell lines
Here we performed transcriptional profiling of the prostate cancer cell lines LNCaP and 22Rv1 comparing non-targeting siRNA treatment versus siRNAs targeting SWI/SNF complex proteins (SMARCA2, SMARCA4, and SMARCB1). Goal was to determine the effect of SWI/SNF knockdown on gene expression in prostate...
ORGANISM(S): Homo sapiens 
2013-07-20 | E-GEOD-40384 | biostudies-arrayexpress
TranscriptomicsTargeting the MLL complex in castration-resistant prostate cancer [expression]
Resistance to androgen deprivation therapies and increased androgen receptor (AR) activity are major drivers of castration-resistant prostate cancer (CRPC). Prior work has focused on targeting AR directly; however, the identification and targeting of co-activators of AR signaling remains an underexp...
ORGANISM(S): Homo sapiens 
2015-03-02 | E-GEOD-60836 | biostudies-arrayexpress
TranscriptomicsThe tumor suppressor gene rap1GAP is silenced by mir-101-mediated EZH2 overexpression in invasive squamous cell carcinoma
Rap1GAP is a critical tumor suppressor gene that is down-regulated in multiple aggressive cancers such as head and neck squamous cell carcinoma, melanoma and pancreatic cancer. However, the mechanistic basis of rap1GAP down-regulation in cancers is poorly understood. By employing an integrative appr...
ORGANISM(S): Homo sapiens 
2011-11-02 | E-GEOD-28501 | biostudies-arrayexpress
Sort   by:  
 Page size