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ProteomicsHBXIP-mediated cell cycle, apoptosis and autophagy participate in the inhibitory effect of Germacrone on gastric cancer cells
As a monocyclic sesquiterpene, Germacrone has remarkable anti-tumor effect in a variety of cancers such as hepatocellular carcinoma, gastric cancer, and breast cancer. However, the mechanism of Germacrone on gastric cancer was still unclear. In our study, Germacrone inhibited gastric cancer cells pr...
ORGANISM(S): Homo Sapiens 
2020-10-14 | PXD021980 |
ProteomicsA proteomic classifier panel for early screening of colorectal cancer
Colorectal cancer (CRC) is a leading cause of cancer-related death. Diagnosis at an early stage can greatly improve the patient outcome. Therefore, developing sensitive and specific non-invasive screening and diagnostic methods has a tremendous potential to combat the disease.
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD042639 | Pride
Plasma proteome biomarker 
ProteomicsA proteomic classifier panel for early screening of colorectal cancer part II
Colorectal cancer (CRC) is a leading cause of cancer-related death. Diagnosis at an early stage can greatly improve the patient outcome. Therefore, developing sensitive and specific non-invasive screening and diagnostic methods has a tremendous potential to combat the disease.
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD042652 | Pride
Plasma proteome biomarker 
ProteomicsDetect the shared protein components between spider dragline silk and silkworm cocoon by Label free quantitative proteomics
The spider major ampullate gland and silkworm silk gland have similar morphological structure and function, so we explored whether there are some common protein components on silks, with three biological replicates for each sample. Dragline silk samples from mature female Trichonephila clavata spide...
ORGANISM(S): Bombyx Mori Trichonephila 
2022-12-09 | PXD038734 |
ProteomicsPhospho-proteomics enables classification of cancer subtypes and nomination of druggable kinases for individual patients of diffuse-type gastric cancer
The diffuse-type gastric cancer (DGC) constitutes a subgroup of gastric cancer with poor prognosis and no effective molecular therapies. Here, we report a phosphoproteomic landscape of DGC derived from 83 tumors together with their nearby tissues. Based on phosphorylation, DGC could be classified in...
ORGANISM(S): Homo Sapiens 
2020-03-31 | PXD018293 |
ProteomicsColleterial glands and ootheca proteome
In this study, the fresh oothecae used for proteomics analysis were obtained from American cockroach. Proteomics and PRM analysis were used for the identification of the oothecal proteins including the structural proteins and key enzymes.
ORGANISM(S): Gryllinae Locusta Migratoria Hierodula Patellifera Periplaneta Americana 
2022-02-22 | PXD031823 |
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