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ProteomicsIDENTIFICATION OF SUMO-2/3 MODIFIED PROTEINS ASSOCIATED WITH MITOTIC CHROMOSOMES
Sumoylation is essential for progression through mitosis, but the specific protein targets and functions remain poorly understood. In this study, we used chromosome spreads to more precisely define the localization of SUMO-2/3 to the inner-centromere and protein scaffold of mitotic chromosomes. We a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-10-07 | MSV000078890 | MassIVE
UnknownElucidating the importance and regulation of key enhancers for human MEIS1 expression.
Not available
S-EPMC9343249 | biostudies-literature
OtherIdentification of SUMO-2/3 modified proteins associated with mitotic chromosomes.
Data from Massive, ID: MSV000078890, PXD ID: PXD001534. File: MM_8A2_SUMO23_mitosis_C_75KDa_v1.mzml. Published as part of Proteomics. 2014 Nov 4 . From the Abstract: {{i}} ... In this study, we used chromosome spreads to more precisely define the localization of SUMO-2/3 to the inner-centromere and...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32310005148 | GPMDB
Resource Reanalysis 
UnknownPPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1.
Not available
S-EPMC4942338 | biostudies-literature
Proteomics,MultiomicsMudPIT analyses of the proteins associated with IFZK3 and IFZK1 in a human multiple myeloma cell line, ARP-1
IKZF1 and IKZF3 are transcription factors highly expressed in myeloma and contribute to myeloma cell survival. To better understand the function of IKZFs, we sought out to identify novel physiologic partners. To this purpose we generated a human MM cell line, ARP-1, stably expressing physiologic l...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-13 | MSV000081712 | MassIVE
ProteomicsSpatial proteomics of the human atherosclerotic microenvironment reveals heterogeneity in intra-plaque proteomes and extracellular matrix remodeling
The heterogeneity of atherosclerotic plaques is critical for their vulnerability to rupture and the associate risk of cardiovascular events. Most proteomic studies have only examined bulk changes, potentially obscuring key spatial differences in protein content and abundance. Here we report a high-r...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-08-13 | PXD072200 | Pride
Human Atherosclerosis Spatial proteomics Myocardium Mouse Lcm L md 
no omics definedChromatin immunoprecipitation of human breast cancer cell line MCF-7 treated with 17beta-estradiol
ChIP-DSL experiments using ER alpha antibody on v1 20k promoter array
ORGANISM(S): Homo sapiens 
2007-03-31 | E-MEXP-984 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse treated by ascending aortic banding on wild type and transgenic mice overexpressing CHF1/Hey2 in the myocardium reveals CHF1/Hey2 promotes physiological hypertrophy in response to pressure overload
We have previously found that overexpression of CHF1/Hey2 in the myocardium prevents the development of phenylephrine-induced hypertrophy. To determine the role of CHF1/Hey2 in pressure overload hypertrophy, we performed ascending aortic banding on wild type and transgenic mice overexpressing CHF1/H...
ORGANISM(S): Mus musculus 
2010-02-17 | E-GEOD-13031 | biostudies-arrayexpress
ProteomicsTargeted and non-targeted mass spectrometry to explore the chemical diversity of the genus Gambierdiscus in the Atlantic Ocean
The 15 strains of Gambierdiscus were cultivated in four separate laboratories. Each laboratory grew their available strains (see sample metadata) in addition to the G. australes strain AUS S080911_1 isolated from Pacific Ocean. Irradiance (70-100 umol photons m-2 s-1) and light/dark cycle (12h:12h)...
ORGANISM(S): Gambierdiscus Silvae (ncbitaxon:1550089) Gambierdiscus Carolinianus (ncbitaxon:864182) Gambierdiscus Australes (ncbitaxon:439317) Gambierdiscus Belizeanus (ncbitaxon:439316) Gambierdiscus Excentricus (ncbitaxon:986170) Gambierdiscus Caribaeus (ncbitaxon:864185) 
2024-02-26 | MSV000094172 | MassIVE
Unknownβ2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's disease.
Not available
S-EPMC5761666 | biostudies-literature
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