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ProteomicsComparative glycomics study of N-glycans in breast cancer cell line MCF7 versus normal cell line
This study designed to characterize the differences in N-glycan expressions between normal and breastcancer cells, MCF10A and MCF7. Permethylated N-glycans released by PNGase F were enriched and then analyzed by LC-ESI/MS. The in-house-developed software GlySeeker was used to search IDs of N-glycan...
ORGANISM(S): Homo sapiens (Human) 
2022-03-02 | PXD010454 | Pride
Lc-esi/ms Breast cancer Mcf7 cell 
ProteomicsSARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal pathogen of the ongoing global pandemic of coronavirus disease 2019 (COVID-19). Loss of smell and taste are new identified symptoms of COVID‐19, and both of these are related to cilia dysfunction. However, the pathological me...
ORGANISM(S): Homo Sapiens 
2022-02-23 | PXD031842 |
ProteomicsExploring the Inflammatory Origins of Gouty Arthritis: Mechanistic Studies Based on Local Lesion Proteomics and Validation
Proteomic analysis of gouty tophi and joint cavity effusion
ORGANISM(S): Homo Sapiens 
2026-03-18 | PXD075785 |
ProteomicsA prokaryotic E2 enzyme imitates the ubiquitin pathway to regulate the antiviral cGAS
The cyclic oligonucleotide-based anti-phage signalling system (CBASS) is a typeof innate prokaryotic immune system. Composed of a cyclic GMP-AMP synthase (cGAS) and CBASS-associated proteins, CBASS utilizes cyclic oligonucleotides to activate antiviral immunity. One major class of CBASS contains a h...
ORGANISM(S): Serratia Marcescens Lct-sm213 
2024-02-27 | PXD050178 |
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