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UnknownA high-quality genome assembly of quinoa provides insights into the molecular basis of salt bladder-based salinity tolerance and the exceptional nutritional value.
Not available
S-EPMC5674158 | biostudies-literature
ProteomicsLC-MS/MS Analysis of the glycosylation of human SIDT1 and SIDT2
We performed a systematic characterization of site-specific N-glycosylation and the corresponding N-glycans of human SIDT1 and SIDT2 using LC-MS/MS.
ORGANISM(S): Homo Sapiens 
2023-07-17 | PXD043824 |
ProteomicsDeciphering aging-related changes based on cross-tissue proteomic profilling
The project aims to investigate the molecular mechanisms of aging by analyzing protein expression and modifications across various tissues in multiple organisms. Using advanced mass spectrometry, the project will collect and compare proteomic profiles from different organs at various ages. By identi...
ORGANISM(S): Mus Musculus 
2025-03-18 | PXD061948 |
ProteomicstRNA-m1A Methylation Regulates the Infection of Magnaporthe oryzae by Supporting Ergosterol Biosynthesis
Ergosterols are essential components of fungal plasma membranes. Inhibitors targeting ergosterol biosynthesis (ERG) genes are critical for controlling fungal pathogens, including Magnaporthe oryzae, the fungus that causes rice blast. In this study we show that the Trm6/Trm61 complex catalyzes dynami...
ORGANISM(S): Pyricularia Oryzae 70-15 
2024-06-07 | PXD051352 |
ProteomicsTailoring an Intravenously Injectable Oncolytic Virus for Augmenting Radiotherapy
Oncolytic viruses (OVs) combined with radiotherapy (RT) have shown promise in clinical trials but remain limited by unsatisfactory efficacy. Key challenges include poor intravenous delivery, insufficient RT-induced DNA damage, and suboptimal anti-tumor immune responses. Herein, we developed a novel ...
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-02-02 | PXD060493 |
ProteomicsFTO deficiency in older livers exacerbates ferroptosis during ischaemia/reperfusion injury by upregulating ACSL4 and TFRC
Older livers are more prone to hepatic ischaemia/reperfusion injury (HIRI), which severely limits their utilization in liver transplantation (LT); however, the potential mechanism remains unclear. Here, we demonstrated older livers exhibit a higher degree of ferroptosis during HIRI. Inhibiting ferro...
ORGANISM(S): Mus Musculus 
2024-04-12 | PXD051387 |
ProteomicsEndothelial FGF13 impairs angiogenesis by accelerating oxygen-independent HIF-1α degradation
Anti-Flag antibody was added to the lysate of HUVECs transfected with Flag-FGF13 for co-immunoprecipitation, and IgG was used as a negative control. LC-MS/MS analysis was carried out by PTM Bio Co., Ltd (Zhejiang, China). The substrate proteins that may bind to FGF13 were screened out according to t...
ORGANISM(S): Homo Sapiens 
2026-06-16 | PXD079802 |
ProteomicsThe p-MYH9/USP22/HIF-1α axis promotes lenvatinib resistance and cancer stemness in hepatocellular carcinoma
To understand the role of HIF1a in lenvatinib resistance, we conducted label-free quantitative proteome analysis in both control and lenvatinib resistance cell lines. This analysis revealed changes in the proteome due to the lenvatinib resistance, providing a valuable reference for further investiga...
ORGANISM(S): Homo Sapiens 
2024-08-29 | PXD055440 |
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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