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Rapid and non-destructive estimation of leaf nitrogen accumulation (LNA) is essential to field nitrogen management. Currently, many vegetation indices have been used for indicating nitrogen status. Few studies systematically analyzed the performance of vegetation indices of winter wheat in estimatin...
Nitrogen deposition is recognized as one of the major threats to the ecosystem function of alpine grasslands on the Qinghai-Tibetan Plateau (QTP). However, few studies have documented the gradient responses of plant species, functional groups, and communities in alpine grassland ecosystems to variou...
Camellia oleifera is an economically important woody oil crop in China, where seed oil quality and yield are critical determinants of commercial value. Although the WD40-repeat transcription factor TTG1 is known to regulate plant secondary metabolism and development, its specific funct...
Microbial communities play a vital role in cadaver decomposition and serve as reliable tools for postmortem interval (PMI) estimation. However, current research focuses primarily on bacterial/fungal communities, though viruses-as Earth's most abundant biological entities-play key roles in biogeochem...

Objective

The present study aimed to investigate the potential role and molecular mechanism of procyanidin B2 (PCB2) in the treatment of multiple sclerosis (MS), with the hope of providing novel strategies for the precision treatment of MS.

Methods

The target genes of PCB2 and the dis...
Background: Increasing attention has been attracted by the role of circular RNAs (circRNAs) in ocular diseases. Previous study has revealed that circ_0005941 (also known as circFTO, an alpha-ketoglutarate-dependent dioxygenase) was upregulated in the vitreous humor of diabetic retinopathy (DR...

Background

Multiple sclerosis (MS) is marked by inflammatory demyelination in the central nervous system (CNS), involving diverse glial populations. This pathological process is associated with inflammation and oxidative stress. Proanthocyanidin B2 (PCB2), with its potent antioxidant propert...
Lipocalin-2 (LCN2), an acute phase protein mainly expressed in astrocytes (Ast), is closely related to the production of inflammatory cytokines following ischemic stroke. During the pathophysiological process of ischemic stroke, the Janus kinase 2/signal transducer and activator of transcription 3 (...
In the process of ischemic stroke (IS), cellular macroautophagy/autophagy and apoptosis play a vital role in neuroprotection against it. Therefore, regulating their balance is a potential therapeutic strategy. It has been proved that hydroxysafflor yellow A (HSYA) has anti-inflammatory and antioxida...
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