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MetabolomicsUtilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis
Characterizing the metabolic changes pertaining to hepatocellular carcinoma (HCC) in patients with liver cirrhosis is believed to contribute towards early detection, treatment, and understanding of the molecular mechanisms of HCC. In this study, we compare metabolite levels in sera of 78 HCC cases w...
MTBLS17 | MetaboLights
MetabolomicsPlant elicitor peptide signalling confers rice resistance to piercing-sucking insect herbivores and pathogens
Rice is a staple food crop worldwide, and its production is severely threatened by phloem-feeding insect herbivores, particularly the brown planthopper (BPH, Nilaparvata lugens), and destructive pathogens. Despite the identification of many BPH resistance genes, the molecular basis of rice resistanc...
2022-02-23 | MTBLS3518 | MetaboLights
UnknownMiR-125b regulates proliferation and apoptosis of nasopharyngeal carcinoma by targeting A20/NF-κB signaling pathway.
Not available
S-EPMC5520883 | biostudies-literature
UnknownReduction of RKIP expression promotes nasopharyngeal carcinoma invasion and metastasis by activating Stat3 signaling.
Not available
S-EPMC4599279 | biostudies-literature
MetabolomicsMultiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights
ProteomicsGlobal lysine crotonylation profiling in the livers of mice
Crotonylation (Cr) is a novel post-transcriptional modification with the potential to regulate multiple biological processes. In order to improve the crotonylation dataset for further study, we performed LC-MS/MS with mouse liver samples to obtain the in vivo crotonylome. Totally, we identified 4607...
ORGANISM(S): Mus Musculus 
2020-01-19 | PXD015645 |
ProteomicsGlobal lysine crotonylation profiling of mouse liver (label-free quantitative proteomic data)
Crotonylation (Cr) is a novel post-translational modification with the potential to regulate multiple biological processes. To improve the crotonylation dataset for further study, we performed label-free LC-MS/MS with mouse liver samples to obtain an in vivo crotonylome. In this study, 11,408 croton...
ORGANISM(S): Mus Musculus 
2020-05-13 | PXD019145 |
ProteomicsProteomic and phosphoproteomic profiling of COVID-19-associated lung injury: a report based on rhesus macaques
Lung is the major organ affected by SARS-CoV-2. To explore the molecular mechanism in the lung after SARS-CoV-2 infection, we performed LC-MS based proteome and phosphoproteome analysis using lung tissue samples separated from rhesus macaques.
ORGANISM(S): Macaca Mulatta 
2021-07-08 | PXD027180 |
ProteomicsProteomic and phosphoproteomic profiling of COVID-19-associated liver injury: a report based on rhesus macaques
Almost 50% of COVID-19 patients have symptoms of liver injury. To explore the molecular mechanism in the livers after SARS-CoV-2 infection, we performed LC-MS based proteome and phosphoproteme analysis using liver tissue samples separated from rhesus macaques.
ORGANISM(S): Macaca Mulatta 
2021-07-08 | PXD027179 |
ProteomicsLabel-free LC-MS/MS of proteins derived from excretory secretory products and positive sera of Clonorchis sinensis of rabbit
The excretory secretory products and positive sera of Clonorchis sinensis were collected for identifying the proteins presented in different infection periods, which specific to the sera of C. sinensis, but not combined with Fasciola hepatica, and Schistosoma japonicum. The White Japanese rabbits we...
ORGANISM(S): Oryctolagus Cuniculus 
PXD028236 |
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