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MetabolomicsSacha inchi oil alleviates gut microbiota dysbiosis and improves hepatic lipid dysmetabolism in high-fat diet-fed rats
Dietary ω-3 polyunsaturated fatty acids (PUFAs) are beneficial for humans against the development of hyperlipidaemia, but the underlying mechanisms are still poorly understood. Here, we demonstrated that oral consumption of sacha inchi oil, which is rich in α-linolenic acid, alleviated dyslipidemia,...
2022-02-21 | MTBLS1225 | MetaboLights
ProteomicsIdentification of OTUD3 interactors in esophageal cancer cell line
Immunoprecipitation of OTUD3 interacting proteins was subjected to SDS-PAGE, silver-stained, and identified by mass spectrometry (MS).
ORGANISM(S): Homo Sapiens 
2021-09-26 | PXD028751 |
ProteomicsSUMOylation fine tunes the transcriptional activity of endothelial HEY1 in the regulation of angiogenesis
Reversible HEY1 SUMOylation is a molecular mechanism that coordinates endothelial angiogenic signaling and angiogenesis, both in physiological and pathological milieus, by fine tuning the transcriptional activity of HEY1. Specifically, S UMOylation facilitates the formation of the HEY1 transcription...
ORGANISM(S): Homo Sapiens 
2023-08-18 | PXD044611 |
ProteomicsIdentification of ATP9A interactors in 293T cell line
Macropinocytosis is an effective strategy against nutrient starvation, which fuels cancer cells grow in nutrient-limited conditions. However, whether and how macropinocytosis contributes to the rapid proliferation of hepatocellular carcinoma cells that frequently exhibit inadequate nutrient supply r...
ORGANISM(S): Homo Sapiens 
2022-12-13 | PXD038797 |
ProteomicsIdentification of ADAM10 interactors and N-glycosylation sites in SK-BR-3 cells
Immunoprecipitation of ADAM10-WT and ADAM10-4NQ interacting proteins were identified by mass spectrometry(MS));purified ADAM10 protein was subjected to Coomassie Blue Staining and LC-MS/MS in order to identify the N-glycosylation sites
ORGANISM(S): Homo Sapiens 
2022-07-16 | PXD035378 |
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