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ProteomicsLysine 2-hydroxyisobutyrylatome profiling reveals extensive lysine 2-hydroxyisobutyrylation in common wheat
In this work, we first analyzed wheat (Triticum aestivum L.) lysine Khib sites by mass spectrometry. A total of 3,348 lysine modification sites from 1,047 proteins were identified in wheat seedlings. The identified Kcr proteins were discovered to be widespread. Bioinformatic data indicated these Kcr...
ORGANISM(S): Triticum aestivum (Wheat) 
2022-12-31 | PXD012666 | Pride
Triticum aestivum l.  post-translational modification  lysine 2-hydroxyisobutyrylation  mass spectrometry  function 
Proteomicssystematic proteomic of 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN)
To obtain the global landscape of Khib in ESCC metastasis, 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN) were subjected to systematic proteomic.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD037295 | Pride
Proteomics Cancer metastasis 
ProteomicsNitric oxide modulates Saccharomyces cerevisiae biofilm formation though regulating the transmembrane protein CTR1 by activating its transcriptional factor MAC1.
Biofilms with immobilized cells in industrial fermentation are beneficial. Encased in extracellular polymeric substance, cells forming biofilms are regulated by various factors. Nitric oxide (NO), as a signaling molecule, recognized as quorum sensing molecule regulating microbe biofilm formation. Re...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-11-12 | PXD010751 | Pride
Transcription factor mac1 Nitric oxide Saccharomyces cerevisiae Biofilm 
ProteomicsPhysiological and proteomic changes in soft wheat seeds during accelerated aging
Wheat (Triticum aestivum L.), one of the most important crops in the world, is a staple food used for making flour, noodles, alcoholic beverages, biofuel and a variety of other products. In wheat, kernel texture and biochemical composition vary with different hardnesses. Previous study of our resear...
ORGANISM(S): Triticum aestivum (Wheat) 
2018-10-08 | PXD009156 | Pride
Tandem mass tag Differentially expressed proteins Wheat Lc-ms/ms 
UnknownCytosolic peptides encoding CaV1 C-termini downregulate the calcium channel activity-neuritogenesis coupling.
Not available
S-EPMC9120191 | biostudies-literature
UnknownCalf Circumference and All-Cause Mortality: A Systematic Review and Meta-Analysis Based on Trend Estimation Approaches.
Not available
S-EPMC12280773 | biostudies-literature
ProteomicsProteomics reveals the inhibitory mechanism of Levodopa against esophageal squamous cell carcinoma
The high recurrence rate and poor survival prospects of esophageal squamous cell carcinoma (ESCC) patients after treatment make the ongoing research on chemoprevention drugs for ESCC particularly important. In helping to solve this problem, we screened a large number of FDA-approved drugs and found ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD013824 | Pride
Mitochondria Levodopa Chemoprevention Esophageal squamous cell carcinoma (escc) 
ProteomicsA proteomic analysis of lysine crotonylation in systemic lupus erythematosus patients
Posttranslational modification (PTM) refers to the process of the covalent processing of translated proteins, as well as the activities and functions of proteins, and it is involved in almost all cellular pathways and processes. Lysine crotonylation (Kcr) is a recently identified PTM and plays a key...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD012966 | Pride
Posttranslational modification Lysine crotonylation Lc-ms/ms 
ProteomicsMolecular mechanism of protein dynamic change in Pacific oyster (Crassostrea gigas) during depuration at different salinities uncovered by mass spectrometry-based proteomics combined with bioinformatics
Pacific oyster (Crassostrea gigas), Depuration, Proteomics, SWATH-MS
ORGANISM(S): Crassostrea Gigas 
2022-05-03 | PXD033573 |
ProteomicsAnalysis of muscular proteomics of deep pressure ulcers reveals JAK2 influence on muscle autophagy and apoptosis
Pressure ulcers (PU) is a complex and serious clinical problem. Deep tissue injury is either the outcome or the trigger of deep PU. However, the cellular and molecular mechanisms that contribute to the pathogenesis of deep PU remain unclear. In this study, the degeneration characteristics, increased...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD009512 | Pride
Proteomics Ischemia/reperfusion injury Deep pressure ulcers Jak2 Autophagy & apoptosis 
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