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ProteomicsHUVEC endosome LCMS - ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes
Complement promotes vascular inflammation in transplant organ rejection and connective tissue diseases. Here we identify ZFYVE21 as a complement-induced Rab5 effector that regulates pro-inflammatory non-canonical NF-B signaling in endothelial cells (EC). In response to membrane attack complexes (MAC...
ORGANISM(S): Homo sapiens (Human) 
2019-04-09 | PXD013381 | Pride
Rab5 mac 
UnknownPrediction of Mortality and Major Adverse Kidney Events in Critically Ill Patients With Acute Kidney Injury.
Not available
S-EPMC9780161 | biostudies-literature
TranscriptomicsExpression profile of 16C ovarian follicle cells
We use DSN normalized RNA-seq to transcriptionally profile FACS sorted 16C ovarian follicle cells. These data provide insights into the developmental control of gene expression programmed gene amplificaton. Follicle cells were isolated from whole ovaries by trypsinization and filtering and stained w...
ORGANISM(S): Drosophila melanogaster 
2011-05-27 | E-GEOD-29526 | biostudies-arrayexpress
GenomicsASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers
ChIP-Seq analysis performed on 5 ASCL1(+) cell lines and 2 ASCL1 (-) cell lines in order to understand the transcriptome of ASCL1 as it pertains to high-grade neuroendocrine lung cancers 5 ASCL1(+) lung cancer cell lines and 2 ASCL1(-) lung cancer cell lines were compared using ChIP-Seq analysis
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-61197 | biostudies-arrayexpress
UnknownEndothelial Cell-Derived Interleukin-18 Released During Ischemia Reperfusion Injury Selectively Expands T Peripheral Helper Cells to Promote Alloantibody Production.
Not available
S-EPMC7035199 | biostudies-literature
UnknownInterferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1.
Not available
S-EPMC5922286 | biostudies-literature
UnknownThe Hormone FGF21 Stimulates Water Drinking in Response to Ketogenic Diet and Alcohol.
Not available
S-EPMC5990458 | biostudies-literature
UnknownEvaluation of image quality with four positron emitters and three preclinical PET/CT systems.
Not available
S-EPMC7728905 | biostudies-literature
UnknownZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes.
Not available
S-EPMC6529429 | biostudies-literature
UnknownThe quality of telemedicine consultations for sexually transmitted infections in China.
Not available
S-EPMC11423847 | biostudies-literature
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