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UnknownChinese herbal medicine Jia Wei Jing Xie Yin (JWJXY) ameliorates psoriasis via suppressing the Th17 cell response.
Not available
S-EPMC9011239 | biostudies-literature
TranscriptomicsDirect reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails
The direct conversion, or trans-differentiation, of non-cardiac cells into cardiomyocytes by forced expression of transcription factors and microRNAs provide promising ways of cardiac regeneration. However, genetic manipulations are still not desirable in real clinical applications. we report the ge...
ORGANISM(S): Mus musculus 
2015-08-23 | E-GEOD-69924 | biostudies-arrayexpress
UnknownRAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes.
Not available
S-EPMC8754306 | biostudies-literature
ProteomicsBlood coagulation and complement activation interact to increase disease activity in systemic lupus erythematosus and coagulation D-Dimer combined with complement C4 is a biomarker of lupus activity
This study was conducted to (1) find deregulation of certain pathways in SLE at multi-omics levels; (2) evaluate the associations among blood coagulation, complement activation, inflammatory responses and SLE disease severity; (3) develop biomarkers to facilitate better the assessment of the likelih...
ORGANISM(S): Homo sapiens (Human) 
2018-10-27 | PXD004443 | Pride
Systemic lupus erythematosus  blood coagulation itraq 
UnknownFacile Transformation from Rofecoxib to a New Near-Infrared Lipid Droplet Fluorescent Probe and Its Investigations on AIE Property, Solvatochromism and Mechanochromism.
Not available
S-EPMC9967153 | biostudies-literature
ProteomicsProtein Lactylation modification and Proteomics Features in Cirrhosis Patients after MSCs Treatment.
Mesenchymal stem cell (MSC) therapy improves liver function in patients with liver cirrhosis. However, the therapeutic mechanism underlying MSC therapy remains unclear. Therefore, this study aimed to elucidate the therapeutic mechanism underlying MSC therapy by analyzing changes in the modification ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD037530 | Pride
Liver cirrhosis  mesenchymal stem cell  cell therapy  lactylation modification  proteomics analysis. 
GenomicsGlobal Reorganization of Chromatin Architecture during Embronic Stem Cell Differentiation
The 3D organization of the genome is important for regulation of diverse nuclear processes ranging from transcription to DNA replication. Knowledge of the higher order chromatin structure is critical for understanding mechanisms of gene regulation by long-range control elements such as enhancers and...
ORGANISM(S): Homo sapiens 
2015-02-18 | E-GEOD-52457 | biostudies-arrayexpress
UnknownComplete mitochondrial genome of Pseudoechthistatus hei (Coleoptera: Cerambycidae: Lamiinae) and its phylogenetic analysis.
Not available
S-EPMC9668276 | biostudies-literature
TranscriptomicsGene expression data from LCMV-specific WT and Tcf7-/- follicular T helper cells
We did microarray experiments to elucidate the transcriptome changes due to TCF-1 deficiency in Tfh cells. These data clearly demonstrate that Tfh-associated genes were down-regulated in TCF-1-null Tfh cells, whereas Th1-associated signatures were up-regulated, indicating that TCF-1 initiates the Tf...
ORGANISM(S): Mus musculus 
2015-07-24 | E-GEOD-65693 | biostudies-arrayexpress
TranscriptomicsDissecting the developmental transcriptomes of rice
Transcriptional programs are important for the development of complex eukaryotic organisms. Suites of genes expressed with temporal and spatial controls by regulatory networks in response to environmental cues are the cornerstone for achieving the specification of morphology and physiology of the ti...
ORGANISM(S): Oryza sativa Indica Group 
2010-01-20 | E-GEOD-19024 | biostudies-arrayexpress
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