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GenomicsTranscription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells
This SuperSeries is composed of the following subset Series: GSE35910: Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells [EBF1] GSE35914: Transcription factor Ebf1 regulates differentiation stage-specific signaling, prolifer...
ORGANISM(S): Mus musculus 
2012-04-02 | E-GEOD-35915 | biostudies-arrayexpress
GenomicsTranscription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells [EBF1]
Transcription factor Ebf1 is an important determinant of early B lymphopoiesis. To gain insight into differentiation stage-specific functions of Ebf1, we conditionally inactivated Ebf1. We found that Ebf1 is required for proliferation, survival and signaling of pro-B cells and peripheral B cell su...
ORGANISM(S): Mus musculus 
2012-04-02 | E-GEOD-35910 | biostudies-arrayexpress
TranscriptomicsGene Expression Circulating B Lymphocytes for Smoking Females
B cells were found to be directly associated with the onset and development of many smoking-induced diseases. However, the in vivo molecular response of B cells underlying the female cigarette smoking remains unknown. Using the genome-wide Affymetrix HG-133A GeneChip® microarray, we compared the gen...
ORGANISM(S): Homo sapiens 
2009-12-25 | E-GEOD-18723 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of B-cells stimulated by different compounds (CIDR GST anti Ig)
Transcription profiling of B-cells stimulated by different compunds (CIDR; GST; anti Ig)
ORGANISM(S): Homo sapiens 
2005-06-30 | E-MEXP-316 | biostudies-arrayexpress
TranscriptomicsscRNASeq of Naïve, GC, plasma, memory B cells sorted from WT and Fip200-deficient mice spleen
We have employed a scRANSeq to study the difference between WT and Fip200-deficient B cell populations from mice spleen 11 days after immunization. FIP200 plays an important role in regulating LC3-dependent and LC3-independent autophage pathway, which is crucial for B cell development and differenti...
ORGANISM(S): Mus musculus 
2025-11-25 | E-MTAB-16123 | biostudies-arrayexpress
GenomicsGenome-wide mapping of EBF1 binding sites in murine pre B-cells
Early B cell factor-1 (Ebf1), a transcription factor expressed in B cells, adipocytes and neuronal cells, has been identified as a determinant in the specification of the B cell lineage in which Ebf1 acts in a regulatory network with the transcription factors E2A and Pax5. To gain insight into the ...
ORGANISM(S): Mus musculus 
2010-05-06 | E-GEOD-19971 | biostudies-arrayexpress
TranscriptomicsCell type-specific induction of mRNA in human B cells and monocytes by IFN-beta
Compared to primary human monocytes in whole blood cultures, few B cells activated STAT1 in response to stimulation of 2000 IU/ml IFN-beta for 45 minutes. Because activation of STAT1 leads to apoptosis induction, we tested the hypothesis that less pro-apoptotic genes are induced in B cells as compa...
ORGANISM(S): Homo sapiens 
2010-10-20 | E-GEOD-23307 | biostudies-arrayexpress
TranscriptomicsGene and microRNA expression data of diffuse large B cell lymphoma from human diagnostic frozen samples
This SuperSeries is composed of the following subset Series: GSE21846: Transcriptional profiling of 29 cases of diffuse large B cell lymphoma GSE21847: miRNA profiling of 29 cases of diffuse large B cell lymphoma GSE21848: miRNA profiling of 36 cases of diffuse large B cell lymphoma Refer to individ...
ORGANISM(S): Homo sapiens 
2011-08-01 | E-GEOD-21849 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of 36 cases of diffuse large B cell lymphoma
miRNA expression data from 36 cases of RCHOP treated DLBCL samples were correlated with clinical variables in order to find miRNA signatures related with outcome. Cases classified according to the cell of origin classsifer (Wright G, Tan B, Rosenwald A, Hurt EH, Wiestner A, Staudt LM. A gene express...
ORGANISM(S): Homo sapiens 
2011-08-01 | E-GEOD-21848 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of 29 cases of diffuse large B cell lymphoma
29 cases of RCHOP treated DLBCL were profiled for miRNA expression. Different integrated annalysis were performed, including mirNA differential expression between cases classified according to the COO signature (see later) and correlation tests between gene and miRNA expression. Cases classified acc...
ORGANISM(S): Homo sapiens 
2011-08-01 | E-GEOD-21847 | biostudies-arrayexpress
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