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ProteomicsDifferential proteomics analysis on plasma from anlotinib-treated advanced non-small cell lung cancer patients
Anlotinib has been demonstrated to be effective in advanced non-small cell lung cancer (NSCLC) patients. DNA-seq- and RNA-seq-based anlotinib molecular mechanism and biomarker screening have been introduced in previous studies. The underlying value of proteomics for anlotinib study is still unclear....
ORGANISM(S): Homo Sapiens 
2020-03-05 | PXD017919 |
TranscriptomicsChemotherapy plus EGFR-TKI as first-line treatment provides better survival for advanced EGFR positive lung adenocarcinoma patients: updated data and exploratory in vitro study
To probe into the potential mechanisms contributing to the strong synergistic interaction between gefitinib and pemetrexed, gene expression profiles of PC-9 cells exposed to gefitinib, pemetrexed or combined treatment were analyzed using microarray technique.
ORGANISM(S): Homo sapiens 
2020-03-12 | E-MTAB-8661 | biostudies-arrayexpress
ProteomicsCD147 monoclonal antibody attenuates abdominal aortic aneurysm formation in angiotensin II-Infused apoE-/- mice
Three biological replicates were performed on the aortic vascular tissue of the experimental group and the control group respectively, and proteomic studies were performed
ORGANISM(S): Mus <genus> 
2022-08-15 | PXD036063 |
ProteomicsProteomic insights into the pathogenesis of intracerebral hemorrhage: The role of blend sign in hematoma expansion
The blend sign on CT imaging is a key predictor of hematoma growth in intracerebral hemorrhage (ICH), yet the underlying pathological mechanisms remain poorly understood. To address this, hematoma specimens from nine ICH patients with blend signs were collected via stereotactic minimally invasive pu...
ORGANISM(S): Homo Sapiens 
2025-08-21 | PXD067588 |
ProteomicsLactylation contributes to colorectal carcinogenesis
To reveal the lactylated proteins in CRC, we analyzed the lactyl-proteome from seven paired biopsies from CRC patients by using mass spectrometry analysis (LC-MS/MS). Meanwhile, we used LC-MS to identify Kla and Kac substrates upon HCT116 cells.
ORGANISM(S): Homo Sapiens 
2022-10-27 | PXD037744 |
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