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GenomicsAn Ezh2 and Ezh1 dual inhibitor, UNC1999, re-shapes the landscape of H3K27me3 versus H3K27ac in MLL-AF9-transformed murine leukemia
Ezh2 and EZH1 are histone H3 lysine 27 (H3K27)-specific methyltransferases. Their hyperactive mutations and overexpression were found in cancer including various hematological malignancies. UNC1999 is a highly selective inhibitor for both enzymes. It suppresses H3K27 tri- and di-methylation globally...
ORGANISM(S): Mus musculus 
2014-10-30 | E-GEOD-62437 | biostudies-arrayexpress
UnknownInteractions Between Climate Mean and Variability Drive Future Agroecosystem Vulnerability.
Not available
S-EPMC11803497 | biostudies-literature
ProteomicsMetaproteomics of Jiuqu starter and fermented grains
To study the characteristics of proteins in Chinese Chixiang-flavor Baijiu fermentation, a label-free quantitative proteomics approach was established to identify proteins in Jiuqu starter and fermented grains.
ORGANISM(S): Fungi Rhizopus Microsporus Bacteria Lactobacillus Helveticus Cirm-bia 103 Saccharomyces Cerevisiae 
PXD014221 |
TranscriptomicsExpression data of MLL-AF9-transformed murine leukemia progenitor cells, following treatment with UNC1999, a dual Ezh1 and Ezh2 inhibitor, or knockdown of EED
Ezh2 and EZH1 are histone H3 lysine 27 specific methyltransferase. Their hyperactive mutations and overexpression were found in cancer including various hematological malignancies. UNC1999 is a highly selective inhibitor for both enzymes. It suppresses H3K27 tri- and di-methylation globally and inhi...
ORGANISM(S): Mus musculus 
2014-10-10 | E-GEOD-62198 | biostudies-arrayexpress
Unknown{110} Surface-Exposed Bi<sub>3.15</sub>Nd<sub>0.85</sub>Ti<sub>3</sub>O<sub>12</sub> Ferroelectric Nanosheet Arrays on Porous Ceramics as Efficient and Recyclable Piezo-Photocatalysts.
Not available
S-EPMC11937749 | biostudies-literature
UnknownA liver-infiltrating CD4+ Tfh1 cell response predicts HCV control, hepatitis, and seroconversion during acute infection.
Not available
S-EPMC12578392 | biostudies-literature
UnknownIn silico screening identifies a novel small molecule inhibitor that counteracts PARP inhibitor resistance in ovarian cancer.
Not available
S-EPMC8044145 | biostudies-literature
UnknownTuning Electrostatic Gating of Semiconducting Carbon Nanotubes by Controlling Protein Orientation in Biosensing Devices.
Not available
S-EPMC8457214 | biostudies-literature
UnknownDesign, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4.
Not available
S-EPMC5895456 | biostudies-literature
UnknownTuning Electrostatic Gating of Semiconducting Carbon Nanotubes by Controlling Protein Orientation in Biosensing Devices.
Not available
S-EPMC10946871 | biostudies-literature
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