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Metabolic reprogramming is a critical driver in the pathogenesis of gastric cancer (GC). However, the intricate regulatory mechanisms that govern this reprogramming and their role in GC progression remain inadequately understood. Here, we have elucidated that Methyltransferase-like 10 (METTL10) is a...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD057247 | Pride
Sepsis is often a cause of mortality in patients admitted to the intensive care unit. Notably, the heart is the organ most susceptible to the impact of sepsis.Mice injected intraperitoneally with LPS solution (20 mg/kg) were designated as the sepsis experimental group, while those injected intraperi...
ORGANISM(S): Mus Musculus 
2024-12-24 | PXD059227 |
Sepsis is often a cause of mortality in patients admitted to the intensive care unit. Notably, the heart is the organ most susceptible to the impact of sepsis.Mice injected intraperitoneally with LPS solution (20 mg/kg) were designated as the sepsis experimental group, while those injected intraperi...
ORGANISM(S): Mus Musculus 
2025-01-07 | PXD059523 |
Metabolic heterogeneity resulting from the intrinsic heterogeneity of human tumors has been shown to cause a myriad of adverse outcomes of tumor therapy, including resistance to chemotherapy, but the mechanisms inside remain largely unknown. Here, we found that the de novo pyrimidine synthesis pathw...
ORGANISM(S): Homo Sapiens 
2025-01-01 | PXD059365 |
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