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MetabolomicsDiagnostic Potential of Plasma IgG N-glycans in Discriminating Thyroid Cancer from Benign Thyroid Nodules and Healthy Controls

BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
ProteomicsSS18/BAFs regulate chromatin accessibility dynamics during pluripotent-somatic transition
The exit from pluripotency or pluripotent-somatic transition (PST) landmarks an event of mammalian development, and is also a representative cell-fate transition model, but remains largely unresolved. Recently, we reported construction of robust JUN-induced PST completed in one cell cycle and whose ...
ORGANISM(S): Mus Musculus 
PXD029277 |
UnknownH3K27ac mediated SS18/BAFs relocation regulates JUN induced pluripotent-somatic transition.
Not available
S-EPMC9204951 | biostudies-literature
TranscriptomicsAnalysis of the transcriptional responses in inflorescence buds of Jatropha curcas exposed to cytokinin treatment
Jatropha curcas L. is a potential biofuel plant. Application of exogenous cytokinin (6-benzyladenine, BA) on its inflorescence buds can significantly increase the number of female flowers, thereby improving seed yield. To investigate which genes and signal pathways are involved in the response to cy...
ORGANISM(S): Jatropha curcas 
2014-12-14 | E-GEOD-54366 | biostudies-arrayexpress
UnknownStructural insights into catalysis and dimerization enhanced exonuclease activity of RNase J.
Not available
S-EPMC4477667 | biostudies-literature
TranscriptomicsDrosophila melanogaster developmental timecourse: wild type, eve, ftz
Transcriptional profiling of developmentally staged D. mel. Embryos for three genotypes: wild type, eve3 and ftz11 For additional information, please see Liu et al., 2009. Abstract: We constructed a large-scale functional network model in Drosophila melanogaster built around two key transcription fa...
ORGANISM(S): Drosophila melanogaster 
2008-12-30 | E-GEOD-14086 | biostudies-arrayexpress
TranscriptomicsMicroRNA-Based Classification of Hepatocellular Carcinoma and Oncogenic Role of miR-517a
Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor due to activation of multiple cellular pathways and molecular alterations. Herein, we report the first molecular classification of 89 HCC based on the expression of 358 microRNAs and integrative genomic analysis. Three main subclass...
ORGANISM(S): Homo sapiens 
2011-02-17 | E-GEOD-20596 | biostudies-arrayexpress
UnknownUbiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein.
Not available
S-EPMC5748463 | biostudies-literature
UnknownGenome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.
Not available
S-EPMC6545159 | biostudies-literature
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
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