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UnknownKun-Qi birth cohort (KQBC) study for the incidence, aetiology and risk factors of chronic kidney disease in Chinese children: a cohort profile.
Not available
S-EPMC12359510 | biostudies-literature
UnknownEfficacy and safety of Ding-Kun-Dan for female infertility patients with predicted poor ovarian response undergoing in vitro fertilization/intracytoplasmic sperm injection: study protocol for a randomized controlled trial.
Not available
S-EPMC5819272 | biostudies-literature
ProteomicsMulti-Omic Signatures of Thyroid Damage in Age-Related Subclinical Hypothyroidism
Age-associated subclinical hypothyroidism (AR-SCH) causes severe structural and functional damage to thyroid glands in aged populations, but the global molecular mechanisms governing AR-SCH pathogenesis are largely unclear. We constructed an exhaustive multi-omic map of thyroid tissues from AR-SCH m...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-28 | PXD080737 | Pride
Subclinical hypothyroidism Mouse Proteomics Multi-omics 
MetabolomicsUPLC-MS-Based Serum Metabolic Profiling Reveals Potential Biomarkers for Predicting Propofol Responsiveness in Females

Although previous studies have shown that certain factors interfere with the sensitivity of propofol, the mechanisms for interindividual variability in response to propofol remain unclear. This study aimed to screen the metabolites to predict patients' sensitivity to propofol and to identify meta...

2021-09-29 | MTBLS2311 | MetaboLights
MetabolomicsLsr2, a novel cyclic di-GMP receptor, regulate the synthesis of keto-mycolic acid and control biofilm formation in mycobacteria

Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
UnknownThe anti-PD-L1/CTLA-4 bispecific antibody KN046 plus lenvatinib in advanced unresectable or metastatic hepatocellular carcinoma: a phase II trial.
Not available
S-EPMC11806070 | biostudies-literature
Proteomicsthe MS data involved in the article "Nuclear ACAT1 orchestrates natural killer cell-dependent antitumor immunity in colorectal cancer"
In this study we aim to explore the metabolic enzyme that affects NK cell function in colorectal cancer, and mainly focus on the mechanism how nuclear ACAT1（Mitochondrial acetyl-CoA acetyltransferase）promotes NK cell infiltration and activation
ORGANISM(S): Homo Sapiens 
2025-03-18 | PXD061959 |
ProteomicsImmunological and Metabolic Characteristics of the Omicron Variants Infection
The Omicron variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in November 2021 in South Africa, has initiated the 5th wave of global pandemics. Here, we systemically examined immunological and metabolic characteristics of Omicron variants infection. We found ...
ORGANISM(S): Cercopithecus aethiops (Green monkey) (Grivet) 
2023-03-11 | PXD037955 | Pride
Cos7 cell hla class ι hepatitis b virus and sars-cov-2 peptides 
UnknownPrediction of hepatic lymph node metastases based on magnetic resonance imaging before and after preoperative chemotherapy in patients with colorectal liver metastases underwent surgical resection.
Not available
S-EPMC9942330 | biostudies-literature
MetabolomicsMetabolic biomarkers of gastric cancer

Plasma samples were analyzed using UPLC-MS/MS untargeted metabolomics. The dataset comprised 144 participants. Partial least squares discriminant analysis (PLS-DA) three-dimensional scores plot distinguishing GC patients from non-GC controls. Metabolic profiling and differential comparison identi...

2026-09-29 | MTBLS12684 | MetaboLights
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