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ProteomicsiTRAQ-based Quantitative Proteomics Analysis Screen for Critical Proteins during Temperature-Responsive Flowering of Crocus sativus
To uncover the underlying mechanism of temperature-responsive flowering in Crocus sativus and unveil flowering regulatory proteins, iTRAQ (isobaric tags for relative or absolute quantitation)-based proteomics were applied to study the differences in protein expression profiles in flowering and non-f...
ORGANISM(S): Crocus sativus 
2021-09-09 | PXD021020 | Pride
Crocus sativus itraq 
ProteomicsiTRAQ-based Quantitative Proteomics Analysis of protein profile response to Pink1 deletion in breast cancer
ITRAQ technique was applied to compare the comprehensive protein expression profiles between MDA-MB-231con and MDA-MB-231Pink1-/- cells, and the original mass spectrum data were searched using Mascot engine against the UniProt database and the decoy database. Proteins were identified to be significa...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD027405 | Pride
Human Pink1 Metabolism Breast cancer 
ProteomicsThe Cancer Cell Target Discovery. Comparing Laboratory Evolution of Expanded DNA Six-Nucleotide Alphabets with Standard Four-Nucleotide Alphabets
Artificial evolvable genetic information systems (AEGIS) are DNA-like molecules that can be copied, support laboratory in vitro evolution (LIVE), and evolve to give AegisBodies, analogs of antibodies. However, unlike DNA aptamers built from four different nucleotides, AegisBodies are built from si...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055115 | Pride
Target determination Aptamer Molecular interactions Cancer cell Unnatural bases 
ProteomicsThe Cancer Cell Target Discovery. Comparing Laboratory Evolution of Expanded DNA Six-Nucleotide Alphabets with Standard Four-Nucleotide Alphabets
Artificial evolvable genetic information systems (AEGIS) are DNA-like molecules that can be copied, support laboratory in vitro evolution (LIVE), and evolve to give AegisBodies, analogs of antibodies. However, unlike DNA aptamers built from four different nucleotides, AegisBodies are built from si...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055130 | Pride
Target determination Aptamer Molecular interactions Cancer cell Unnatural bases 
ProteomicsThe Cancer Cell Target Discovery. Comparing Laboratory Evolution of Expanded DNA Six-Nucleotide Alphabets with Standard Four-Nucleotide Alphabets
Artificial evolvable genetic information systems (AEGIS) are DNA-like molecules that can be copied, support laboratory in vitro evolution (LIVE), and evolve to give AegisBodies, analogs of antibodies. However, unlike DNA aptamers built from four different nucleotides, AegisBodies are built from si...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055107 | Pride
Target determination Aptamer Molecular interactions Cancer cell Unnatural bases 
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