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We used three siRNAs to silence HSPA8 in MDA-MB-468 cells, and then used RNA-seq to compare HSPA8 knockdown cells with the controls.
ORGANISM(S): Homo sapiens 
PFOS and PFOA are persistent organic pollutants known to impair human reproduction, but their effects and molecular mechanisms on human sperm remain unclear. Here, we conducted comprehensive proteomic and phosphoproteomic profiling of human sperm exposed to PFOS and PFOA during capacitation to provi...
ORGANISM(S): Homo Sapiens 
Although sperm supply half the genomic material necessary for generating viable offspring in sexual reproduction, the core molecular mechanisms underlying their formation remain largely unelucidated. Here, we demonstrate that leucine-rich repeat-containing 71 (LRRC71) is essential for spermatogenesi...
ORGANISM(S): Mus Musculus 
Aim to identify the IRF1 acetylation site by KAT8 in cotransfected HEK293T cells
ORGANISM(S): Homo Sapiens 
2022-12-05 | PXD038568 |
V5-TurboID-KAT8-expressing A375 stable cells were treated with biotin and then underwent streptavidin purification and mass spectrometry.
ORGANISM(S): Homo Sapiens 
2022-12-05 | PXD038565 |
Skull-base chordoma (SBC) is a rare, aggressive bone cancer with a high recurrent rate. Genomic studies of SBC have improved our understanding of the disease’s biology. However, the molecular biological characteristics and the effective therapy of SBC remain unknown. Here, we carried out an integrat...
ORGANISM(S): Homo Sapiens 
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