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We conducted HPLC-MS analysis of the protein mix immunoprecipitated by SIRT7 antibody under non-IR and 8 Gy X-ray irradiation to identify the interacting proteins of SIRT7 in HaCaT cells.
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD033924 | Pride

Background

ADSCs and growth factor-based therapies are widely investigated for diabetic wound healing. However, the clinical translation of ADSCs is limited by their biological instability under hyperglycemic conditions, while exogenous growth factors face challenges such as short half-life ...
Leukemia is a leading cause of cancer deaths in the developed countries. Great efforts have been undertaken in search of diagnostic biomarkers of leukemia. However, leukemia is highly complex and heterogeneous, involving interaction among multiple molecular components. Individual molecules are not n...

Background

Epithelial-to-Mesenchymal Transition (EMT) induced by glucose in human peritoneal mesothelial cells (HPMCs) is a major cause of peritoneal membrane (PM) fibrosis and dysfunction.

Methods

To investigate serum response factor (SRF) impacts on EMT-derived fibrosis in PM, we is...
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