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Extracellular matrix (ECM) remodeling is strongly linked to Alzheimer’s disease (AD) risk, but its functions are not fully understood. Here, we found that medial prefrontal cortex (mPFC) injection with chondroitinase ABC (ChABC) to remodel ECM reverses short-term memory loss and reduces Aβ depositio...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD046784 | Pride
AC16 cells were transfected with a plasmid designed to overexpress TRIM38, along with a negative control plasmid. After confirming successful transfection, the cells were stimulated with phenylephrine (PE) to induce a cardiac hypertrophy model. Subsequently, ubiquitination analysis was performed on ...
ORGANISM(S): Homo sapiens (Human) 
2025-02-19 | PXD060763 | Pride

Mature milk, as a nutrient-rich endogenous metabolite, has various beneficial effects on the human body. In order to investigate the specific nutrients provided by different dairy products to humans, we used UHPLC-Q-TOF MS to analyze the highly significantly differentially expressed metabolites i...

2023-08-21 | MTBLS6777 | MetaboLights
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