Astrocyte - OmicsDI

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Unknown (4814)
Transcriptomics (1364)
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Proteomics (275)
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Organisms

Mus musculus (898)
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synthetic construct (7)
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prokaryotic environmental samples (1)

Organisms

Mus musculus (643)
Homo sapiens (320)
Rattus norvegicus (47)
Drosophila melanogaster (5)
Macaca mulatta (4)
Mus (3)
Caenorhabditis elegans (2)
Pleurodeles waltl (1)
Taeniopygia guttata (1)
Schmidtea mediterranea (1)
Callithrix jacchus (1)
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Clostridium butyricum (1)
Xenopus laevis (1)
unidentified (1)
Sus scrofa (1)
Toxoplasma gondii (1)
Ovis aries (1)

Repository

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Tissue

Brain (96)
Astrocyte (61)
Cell culture (48)
Microglial cell (14)
Astrocyte of the cerebral cortex (12)
Neuron (9)
Neuron of cerebral cortex (7)
Permanent cell line cell (6)
Oligodendrocyte (5)
Blood plasma (5)
Primary cell (5)
Astrocyte cells (4)
Cerebrospinal fluid (4)
Mature astrocyte (4)
Blood cell (4)
Pericyte cell (3)
Cerebral cortex neuron (3)
Macrophage (3)
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Epithelial cell (3)
Blood (3)
Astroglial cell (2)
SVGp12 cell (2)
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Disease

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Amyotrophic lateral sclerosis (5)
Huntington Disease (4)
Disease free (4)
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Breast cancer (3)
Normal (2)
Glaucoma (2)
Oligodendroglioma (2)
Not Available (2)
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Cancer (2)
Multiple sclerosis (2)
Neurodegenerative disease (2)
Wounds and Injuries (2)
HIV-associated dementia (1)
Oligodendroglioma (1)
Progressive myoclonus epilepsy 1A (1)
Fetal alcohol syndrome (1)
Amyotrophic lateral sclerosis type 6 (1)
Mucinous pancreas adenocarcinoma (1)
Glioblastoma classical subtype (1)
IDH-wildtype glioblastoma (1)
Acute stress disorder (1)
Spinal cord disease (1)
High grade glioma (1)

Technology Type

Mass Spectrometry (187)
Shotgun proteomics (89)
Bottom-up proteomics (40)
Data-independent acquisition (22)
Affinity purification coupled with mass spectrometry proteomics (17)
Data-dependent acquisition (14)
Gel-based experiment (12)
Mass spectrometry (11)
SWATH MS (11)
Top-down proteomics (7)
HDMSE (5)
Mass spectrometry assay (2)
EI (2)
ESI (2)
SRM/MRM (2)
Proteogenomics (1)
Mass spectrometry imaging (1)
Immunopeptidomics (1)
DiaPASEF (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (28)
Illumina HiSeq 2500 (18)
NextSeq 500 (13)
Illumina HiSeq 2000 (7)
NextSeq 550 (6)
NextSeq 2000 (5)
Illumina NovaSeq X (4)
Qubit 4.0 Fluorometer/ Agilen 5300 Fragment Analyzer (2)
Desktop (2)
Scann Array Express (2)
HiSeq X Ten (2)
Illumina HiSeq 4000 (2)
-- (1)
Qubit 4.0 and TapeStation (1)
Element AVITI (1)
Bioinformatics Core Facility, Centre for Molecular Medicine, CEITEC Masaryk University (1)
Cell culture laboratory, BSL-3 lab (1)
Library preparation kit (1)
RNA isolation laboratory (1)
BSL-3 laboratory (1)
Bacteriological Laboratory (1)
Quantseq FWD kit (Lexogen, Austria) was used to prepare libraries for NGS. Reverse transcription of RNA, amplification of libraries, quality control of libraries and purification were performed exactly as described in manual provided with kit. (1)
RNAeasy kit (1)
Cell culture lab (1)
Not applicable (1)
G2500A GeneArray scanner [Agilent Technologies] (1)
ScanArray 5000 [PerkinElmer] (1)
GenePix Personal 4100A [Axon Instruments] (1)
NextSeq 1000 (1)
AB 5500xl Genetic Analyzer (1)

Publication Date

2025 (220)
2026 (181)
2024 (174)
2021 (156)
2023 (153)
2022 (135)
2020 (85)
2016 (80)
2012 (76)
2015 (67)
2013 (63)
2018 (62)
2017 (54)
2014 (54)
2019 (53)
2011 (52)
2010 (45)
2008 (38)
2009 (24)
2007 (22)
2006 (7)
2002 (5)
2005 (3)

UNIPROT ID/AC

P78352 (1)
Q13554 (1)
P50391 (1)
Q03169 (1)
P17861 (1)
Q13018 (1)
P04628 (1)
Q06787 (1)
P41221 (1)
Q14318 (1)
Q9Y618 (1)
O00755 (1)
O14936 (1)
O95388 (1)
P49768 (1)
P08069 (1)
P05019 (1)
P03372 (1)
P17655 (1)
Q9Y5W5 (1)
Q8TCB0 (1)
P04156 (1)
O75460 (1)
P98155 (1)
Q13492 (1)
Q8N8S7 (1)
Q13976 (1)
Q13541 (1)
P25054 (1)
Q99618 (1)

ENSEMBL ID

ENSMUSP00000140201 (1)
ENSMUSP00000141542 (1)
ENSMUSG00000090272 (1)
ENSMUSP00000141637 (1)
ENSMUSG00000027651 (1)
ENSMUSG00000021039 (1)
ENSMUSP00000141097 (1)
ENSMUSG00000098557 (1)

CHEBI ID

CHEBI:16027 (6)
CHEBI:422 (5)
CHEBI:5656 (2)
CHEBI:4167 (2)
CHEBI:29101 (2)
CHEBI:32816 (2)
CHEBI:15422 (2)
CHEBI:16761 (2)
CHEBI:16908 (2)
ChEBI:16247 (1)
CHEBI:15724 (1)
CHEBI:18139 (1)
CHEBI:35940 (1)
CHEBI:28384 (1)
CHEBI:29256 (1)
CHEBI:17433 (1)
CHEBI:7872 (1)
CHEBI:15986 (1)
CHEBI:7347 (1)
CHEBI:17739 (1)
CHEBI:28920 (1)
CHEBI:15421 (1)
CHEBI:36999 (1)
CHEBI:15701 (1)
CHEBI:16044 (1)
CHEBI:15989 (1)
CHEBI:17166 (1)
CHEBI:16934 (1)
CHEBI:18202 (1)
CHEBI:15947 (1)

Metabolite Name

Tyramine (5)
Uric acid (5)
Citric acid (4)
Oleamide (4)
Palmitic acid (4)
Uracil (4)
Inosine (4)
Pinitol (3)
Biphenyl (3)
Behenic acid (3)
Erythronic acid (3)
Chenodeoxycholic acid (3)
Norvaline (3)
Thymine (3)
Gluconic acid (3)
Tryptamine (3)
Kynurenic acid (3)
Succinic acid (3)
Allantoin (3)
Cholesterol (3)
Pantothenic acid (3)
L-Tyrosine (3)
Deoxycholic acid (3)
L-Tryptophan (3)
Glycerol 3-phosphate (3)
Hypoxanthine (3)
Adenine (3)
Guanine (3)
Citrulline (3)
Niacinamide (3)

First Public Date

2025 (203)
2024 (181)
2026 (158)
2023 (126)
2021 (120)
2022 (103)
2020 (89)
2014 (67)
2019 (46)
2017 (46)
2018 (40)
2015 (15)
2016 (14)
2013 (2)

Modelling Approach

Ordinary differential equation model (1)

Lab affiliation

Paris-Saclay Institute of Neuroscience, Team Melki, CNRS, Gif-sur-Yvette, France (8)
First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China (5)
DZNE Munich, Neuroproteomics, Feodor-Lynen-Str. 17, 81377 München, Germany (4)
Institute of Neuronal Cell Biology Technical University of Munich Germany (3)
Translational Biomarker Group, University of Geneva, Geneva, Switzerland (2)
Navarrabiomed-Clinical Neuroproteomics Laboratory, IdisNA, Proteored-ISCIII (2)
Lab of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, SP, Brazil (2)
Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA (2)
Department for Drug Design and Pharmacology, University of Copenhagen (2)
Louisiana Tech University School of Biological Sciences 1 Adams Blvd. Ruston, LA, 71272 (1)
Developmental Neurobiology, Max Planck Institute of Psychiatry, Munich, Germany (1)
Department of Pediatrics University of Maryland, School of Medicine (1)
Associate Professor, Department of Neurology, Yale University School of Medicine (1)
associate professor of neurology Institute for cell engineering Johns hopkins university school of medicine (1)
Federal State Institution V. P. Serbsky Federal Medical Research Center of Psychiatry and Narcology National Scientific Research Centre on Addictions of the Ministry of Healthcare of the Russian Federation, 119002 Moscow, Russian Federation (1)
Roskamp Institute, Neurodegenerative Disease and Proteomics Lab, Sarasota, FL (1)
Heidelberg University Hospital, Department of Neurology (1)
School of Life Science & Research Center for Natural Peptide Drugs, Shaanxi Engineering & Technological Research Centre for Conservation & Utilization of Regional Biological Resources, Yanan University (1)
Max-Planck-Institute for Multidisciplinary Sciences Bioanalytical Mass Spectrometry Group Am Fassberg 11 D-37077 Goettingen Germany (1)
The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK (1)
Srikant Rangaraju, MD MS Associate Professor Department of Neurology Vascular Neurology Division Emory University (1)
Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, 2610 Wilrijk, Belgium (1)
Department of Quantitative Biomedicine, University of Zurich, Switzerland (1)
University of South Carolina School of Medicine (1)
Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA (1)
University Magdeburg, Institut of Exptl. Internal Medicine Leipziger Str. 44 39130 Magdeburg, Germany (1)
Department for Biochemistry and Molecular Biology University of Southern Denmark Odense, Denmark (1)
Tanz Centre for Research in Neurodegenerative Diseases, Faculty of Medicine, University of Toronto (1)
Institute of Genetics and Developmental Biology, Chinese Acadamy of Sciences (1)
Neuron Glia Biology in Health and Disease Group, iMed.Ulisboa, Faculty of pharmacy, University of Lisbon, Lisbon, Portugal (1)

IsPrivate

False (3)

Model Flag

Non Kinetic (2)

Classification

protozoa (1)
bacteria (1)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (333)
RNA-seq of coding RNA (79)
ChIP-seq (18)
RNA-seq of coding RNA from single cells (14)
RNA-seq of total RNA (8)
Other (6)
Methylation profiling by array (6)
ChIP-chip by tiling array (5)
Transcription profiling by RT-PCR (5)
Unknown experiment type (4)
Cell line - High-throughput sequencing (4)
RNA-seq of non coding RNA (4)
Genotyping by array (3)
Comparative genomic hybridization by array (3)
MicroRNA profiling by high-throughput sequencing (2)
ATAC-seq (2)
Single nucleus RNA sequencing (2)
MicroRNA profiling by array (2)
Transcription profiling by SAGE (1)
Cell line - Single-cell sequencing (1)
Baseline (1)
Differential (1)
RIP-chip by array (1)
One-color microarray (1)
Animal - Single-cell sequencing (1)
Translation profiling (1)
Animal - High-throughput sequencing (1)
RNAi profiling by array (1)
MicroRNA profiling by high throughput sequencing (1)
Spatial transcriptomics by high-throughput sequencing (1)

Release Date

2025 (622)
2022 (576)
2023 (527)
2024 (493)
2021 (478)
2020 (381)
2019 (301)
2018 (300)
2017 (238)
2016 (228)
2015 (182)
2014 (180)
2012 (147)
2013 (138)
2011 (116)
2026 (111)
2010 (85)
2008 (80)
2009 (55)
2007 (37)
2006 (12)
2005 (10)
2004 (9)
2002 (6)
2003 (5)
2001 (4)
1998 (4)
2000 (1)
1996 (1)

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Fasudil may alleviate alcohol-induced astrocyte damage by modifying lipid metabolism, as determined by metabonomics analysis

Alcohol dependence is a chronic, relapsing encephalopathy characterized by compulsive craving for alcohol, loss of control over alcohol use, and the presence of negative emotions and physical discomfort when alcohol is unavailable. Harmful use of alcohol is one of the greatest risk factors for de...

2023-05-15 | MTBLS5071 | MetaboLights

Proteome of human and mouse astrocytes and astrocyte-conditioned medium

ORGANISM(S): Homo Sapiens Mus Musculus

2025-02-05 | PXD060495 |

Inflammatory mediators alter astrocyte genomic profiles and G-protein receptor evoked calcium signaling

Inflammation features in diverse central nervous system disorders such as stroke, trauma, neurodegeneration, infection and autoimmunity. To better understand how inflammatory mediators may alter astrocyte functions, we examined the effects of transforming growth factor-Î²1 (TGF-Î²1), lipopolysacchar...

ORGANISM(S): Mus musculus

2012-10-18 | E-GEOD-36089 | biostudies-arrayexpress

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity

Astrocytes, the most abundant cells in the central nervous system, promote synapse formation and help refine neural connectivity. Although they are allocated to spatially distinct regional domains during development, it is unknown whether region-restricted astrocytes are functionally heterogeneous. ...

ORGANISM(S): Mus musculus

2014-05-02 | E-GEOD-55054 | biostudies-arrayexpress

Proteomics of TurboID-induced biotinylated proteins from astrocyte and astrocyte endeet after acute peripheral inflammation

The brain vasculature is tightly regulated to control the exchange of substances between the periphery and the brain parenchyma at an interface called the blood-brain barrier (BBB). Astrocytes are glial cells that wrap the brain vasculature with a specialised structure called the endfoot, which is a...

ORGANISM(S): Mus musculus (Mouse)

2025-09-11 | PXD056232 | Pride

Mouse Brain Dia Ip Endfoot Isolation Astrocyte

Developmental alcohol exposure leads to a persistent change on astrocyte secretome

Glial cells are central players in the pathogenesis of neurodevelopmental disorders like Fetal Alcohol Spectrum Disorder (FASD). Ethanol can modulate glial differentiation and astrocyte function imposing dramatic changes to the developing brain. Since ethanol can affect a vast number of intracellula...

ORGANISM(S): Mustela putorius furo (European domestic ferret) (Mustela furo)

2016-02-15 | PXD002787 | Pride

Astrocytes Secretome Ethanol Fasd

Mouse brain perivascular astrocyte endfoot proteome

Proteome analysis of isolated mouse brain blood vessels and perivascular astrocyte endfeet (PV-AEF) using DIA.

ORGANISM(S): Mus Musculus (mouse)

2023-11-04 | PXD037949 | JPOST Repository

MartínJiménez2017 - Genome-scale reconstruction of the human astrocyte metabolic network

MartínJiménez2017 - Genome-scale reconstruction of the human astrocyte metabolic network This model is described in the article: Genome-Scale Reconstruction of the Human Astrocyte Metabolic Network. Martín-Jiménez CA, Salazar-Barreto D, Barreto GE, González J. Front Aging Neur...

2017-05-18 | MODEL1608180000 | BioModels

Effects of Hsp72 on astrocyte activation following stroke in the mouse

Astrogliosis is a hallmark of the response to brain ischemia, comprised of changes in gene expression and morphology. Hsp72 protects from cerebral ischemia, and although several mechanisms of protection have been investigated, effects on astrocyte activation are unknown. To identify potential mecha...

ORGANISM(S): Mus musculus

2013-01-11 | E-GEOD-28731 | biostudies-arrayexpress

Corticosterone regulation of mRNAs and and corresponding RU486 antagonism in astrocytes in vitro

Analysis of mRNA gene expression changes mediated by natural glucocorticoid ligand corticosterone in mouse cortical primary astrocyte cultures; also, parallel analysis of RU486 (mifepristone) antagonism of corticosterone-mediated mRNA changes. Total RNA obtained from astrocyte cultures subjected to ...

ORGANISM(S): Mus musculus

2013-01-09 | E-GEOD-39270 | biostudies-arrayexpress

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