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UnknownGenome-Wide Identification, Expression Analysis, and Subcellular Localization of Carthamus tinctorius bHLH Transcription Factors.
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S-EPMC6627405 | biostudies-literature
ProteomicsUrinary Proteomic Profiles of Anterior Cruciate Ligament Reconstruction Patients
A total of 30 ACLR patients, at least 9 months post-surgery, were recruited. Patients were divided into RTS and non-RTS groups based on their ability to return to sport, recovery to pre-injury Tegner levels, and a leg symmetry index of 85% on the single-leg hop test. Urine samples were analyzed usin...
ORGANISM(S): Homo Sapiens 
2025-02-19 | PXD060941 |
MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
ProteomicsUBA2-High Osteosarcoma Suppresses Immune Infiltration by Autophagy-Mediated MHC-I Degradation
Osteosarcoma (OS) responds poorly to immune-checkpoint blockade (ICB), and the molecular drivers of its immune-cold state remain unclear. Using multi-omics analyses, we identified an immune-cold OS subtype characterized by enrichment of protein SUMOylation and found the SUMO E1 subunit UBA2 as a key...
ORGANISM(S): Homo Sapiens 
2026-01-28 | PXD073700 |
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