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TranscriptomicsmRNA Sequencing of skeletal muscle genes in wildtype and BCATm (BCAT2) KO mice
Consumption of a protein containing meal by a fasted animal promotes protein accretion in skeletal muscle, in part through leucine stimulation of protein synthesis and indirectly through repression of protein degradation mediated by its metabolite, α-ketoisocaproate. Mice lacking the mitochondrial ...
ORGANISM(S): Mus musculus 
2015-12-11 | E-GEOD-68915 | biostudies-arrayexpress
UnknownThe efficacy and safety of combining different Chinese patent medicines with conventional Western drugs in the treatment of pediatric allergic rhinitis: network meta-analysis.
Not available
S-EPMC12695863 | biostudies-literature
UnknownEfficacy of the tetravalent protein COVID-19 vaccine, SCTV01E: a phase 3 double-blind, randomized, placebo-controlled trial.
Not available
S-EPMC11269576 | biostudies-literature
ProteomicsDDX5-sIL-36R in keratinocytes controls skin inflammation
The DEAD-box (DDX) proteins function in diverse cellular processes including RNA alternative splicing, and are linked to immune-mediated diseases. However, little is known about the roles of DDXs in skin inflammatory diseases. Here, we show that DDX5, one of the founding members of the DDX RNA helic...
ORGANISM(S): Homo Sapiens 
2020-09-09 | PXD021379 |
UnknownNeoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial.
Not available
S-EPMC6145832 | biostudies-literature
ProteomicsProteome overview of exosome derived from plasma of cows infected with Mycobacterium bovis
Bovine tuberculosis (bTB), primarily caused by Mycobacterium bovis (M. bovis), is a globally zoonotic disease with significant economic impacts. Plasma exosomes have been extensively used for investigating disease processes and exploring biomarkers. While mass spectrometry (MS)-based proteomic analy...
ORGANISM(S): Bos Taurus 
2024-06-17 | PXD048167 |
ProteomicsTranscriptome and iTRAQ proteomic analysis reveal the molecular mechanism of anti- Candida albicans action of trichoderma acid, a potent novel drug candidate
Candida albicans has become one of the main pathogens of fungal infection, which causes great threaten to human health. Hence, it is urgent to develop new anti- C. albicans drugs. A compound named as trichoderma acid was isolated from Trichoderma spirale , which showed stronger inhibitory effect tow...
ORGANISM(S): Candida Albicans 
2021-05-06 | PXD025834 |
ProteomicsProteomics raw data of APEC-OMV isolated from APEC (AE17) and APEC-OMV isolated from APEC infected DF-1 cells
APEC-OMV has complex proteomics. In order to screen the key virulence factors of APEC-OMV, comparative proteomics between APEC-OMV isolated from APEC and APEC-OMV isolated from APEC infection with cells was carried out, laying a good foundation for the study of the pathogenicity and pathogenic mecha...
ORGANISM(S): Escherichia Coli 
2021-10-25 | PXD029347 |
ProteomicsProteomics and phosphoproteomics reveal dysregulated kinases and associated pathway in liver fibrosis
Liver fibrosis is the initial stage of most liver diseases, and it is also a pathological process involving the liver in the late stages of many metabolic diseases. Therefore, it is important to systematically understand the pathological mechanism of liver fibrosis and seek therapeutic approaches fo...
ORGANISM(S): Mus Musculus 
2025-01-16 | PXD059906 |
ProteomicsDDX5 inhibits hyaline cartilage fibrosis and degradation in osteoarthritis via alternative splicing and G-quadruplex unwinding
Hyaline cartilage fibrosis is one of the important reasons for the poor prognosis of advanced osteoarthritis (OA), and is the main factor leading to joint stiffness and deformity. However, the mechanism of hyaline cartilage fibrosis remains largely unclear. Here we found that DDX5, one of the foundi...
ORGANISM(S): Mus Musculus 
2024-03-13 | PXD050571 |
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