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GenomicsGemone-wide maps of PRC2 complex components and chromatin states in prostate cancer cell lines
We report the high-throughput profiling of PRC2 core subunits chromatin states and histone modifications in two prostate cancer cell lines, androgen-dependent cells LNCaP and androgen-independent cells LNCaP-abl (abl). By obtaining over 1 billion bases of sequence from chromatin immunoprecipitated D...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-39459 | biostudies-arrayexpress
ProteomicsGPI-Anchored Ligand-BioID2-Tagging System Identifies proteins Mediating Zika Virus Entry
Identification of host factors facilitating pathogen entry is critical for preventing infectious diseases. Here, we report a tagging system consisting of a viral receptor-binding protein (RBP) linked to BioID2, which is expressed on the cell surface via a GPI anchor. Using VSV or Zika virus (ZIKV) R...
ORGANISM(S): Homo Sapiens 
2022-10-12 | PXD037307 |
UnknownThe association between multimorbidity and intrinsic capacity decline among older adults: the mediating role of frailty.
Not available
S-EPMC12853617 | biostudies-literature
UnknownFBXO5-mediated RNF183 degradation prevents endoplasmic reticulum stress-induced apoptosis and promotes colon cancer progression.
Not available
S-EPMC10784456 | biostudies-literature
ProteomicsIdentification of the indisulam-regulated proteins in AGS cells using label-free quantitative proteomics
In this project, we used label-free quantitative proteomics to identify proteins that are differentially regulated by indisulam in the gastric cancer AGS cell line.
ORGANISM(S): Homo Sapiens 
2024-10-09 | PXD056709 |
UnknownSingle-cell transcriptome analysis indicates fatty acid metabolism-mediated metastasis and immunosuppression in male breast cancer.
Not available
S-EPMC10495415 | biostudies-literature
ProteomicsLithocholic acid targets TULP3-Sirtuins to deacetylate v-ATPase and activate AMPK
Lithocholic acid (LCA), accumulated in mammals during calorie restriction (CR), can activate AMP-activated protein kinase (AMPK) and slow down ageing1. However, how LCA is signalled to activate AMPK and elicit the biological effects is unclear. Here, we show that LCA can enhance the activity of sirt...
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-09-16 | PXD056134 |
ProteomicsProteomics dataset of COVID-19 and control patients
Proteomics dataset of COVID-19 and control patients
ORGANISM(S): Homo Sapiens 
2021-10-14 | PXD029023 |
ProteomicsThe aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
The activity of 5’-adenosine monophosphate-activated protein kinase (AMPK) is inversely correlated with the cellular availability of glucose. When glucose levels are low, the glycolytic enzyme aldolase is not bound to fructose-1,6-bisphosphate (FBP) and, instead, signals to activate lysosomal AMPK. ...
ORGANISM(S): Oryctolagus Cuniculus 
2022-08-10 | PXD035968 |
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