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UnknownSuppression of Fusarium wilt of cucumber by ammonia gas fumigation via reduction of Fusarium population in the field.
Cucumber plants subjected to consecutive monoculture for 9 years were found to suffer from severe Fusarium wilt disease, caused by the soil-borne fungus Fusarium oxysporum f. sp. Cucumerinum J. H. Owen. In the present study, greenhouse experiments were performed to evaluate the influence of ammonia ...
S-EPMC5322401 | biostudies-literature
UnknownIdentification of core genes and pathways in type 2 diabetes mellitus by bioinformatics analysis.
Type 2 diabetes mellitus (T2DM) is a metabolic disorder. Numerous proteins have been identified that are associated with the occurrence and development of T2DM. This study aimed to identify potential core genes and pathways involved in T2DM, through exhaustive bioinformatic analyses using GSE20966 m...
S-EPMC6691242 | biostudies-literature
UnknownFBXO9 mediated the ubiquitination and degradation of YAP in a GSK-3β-dependent manner.
The Hippo signaling pathway effector YAP (Yes-associated protein) serves as a critical transcriptional regulator involved in a wide range of biological processes, including oncogenesis. Despite its potential as a therapeutic target, pharmacologically targeting the Hippo/YAP axis remains challenging,...
S-EPMC12509758 | biostudies-literature
UnknownPhotoreceptor-targeted extracellular vesicles-mediated delivery of Cul7 siRNA for retinal degeneration therapy.
Rationale: Photoreceptor loss is a primary pathological feature of retinal degeneration (RD) with limited treatment strategies. RNA interference (RNAi) has emerged as a promising method of gene therapy in regenerative medicine. However, the transfer of RNAi therapeutics to photoreceptors and ...
S-EPMC11388070 | biostudies-literature
UnknownInhibition of Cyclin-dependent Kinase 2 Signaling Prevents Liver Ischemia and Reperfusion Injury.

Background

Liver ischemia and reperfusion injury (IRI) is a major complication of liver transplant, hepatectomy, and hemorrhagic shock. The cyclin-dependent kinase 2 (CDK2) acts as a pivotal regulator of cell cycle and proliferation.

Methods

This study evaluated the modulation and the...
S-EPMC6433525 | biostudies-literature
UnknownEvery cloud has a silver lining: DeepSeek's light through acute respiratory distress syndrome shadows.
Not available
S-EPMC11898352 | biostudies-literature
UnknownPituitary involvement in ANCA-associated vasculitis: Case report and literature review.
The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is an rare autoimmune condition characterized by inflammatory cell infiltration causing necrosis of small blood vessels. Pituitary involvement is uncommon in AAV and it can occur at any point during AAV. The main clinical man...
S-EPMC12851694 | biostudies-literature
UnknownEfficiency of Cone-Beam Computed Tomography-Based Personalized Microimplant-Assisted Rapid Palatal Expansion in Patients With Maxillary Transverse Deficiency and Thin Palatal Bone.

Introduction and aims

Maxillary transverse deficiency (MTD) affects approximately 10% of adults, but conventional expansion treatments are often ineffective and risky in mature patients due to suture fusion. Although microimplant-assisted rapid palatal expansion (MARPE) improves outcomes, it...
S-EPMC12719730 | biostudies-literature
ProteomicsiTRAQ analysis of Plac9-overexpressed 16HBE cell line
Proteomic analysis of cell proliferation and cell motility in human bronchial epithelium induced by Placenta-specific 9
ORGANISM(S): Homo Sapiens 
2020-05-13 | PXD019147 |
UnknownCharacterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein.

Background

The usefulness of available vaccine and serological tests for leptospirosis is limited by the low cross-reactivity of antigens from numerous serovars of pathogenic Leptospira spp. Identification of genus-specific protein antigens (GP-Ag) of Leptospira would be important for develo...
S-EPMC2632671 | biostudies-literature
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